DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment magu and test-1

DIOPT Version :9

Sequence 1:NP_610548.2 Gene:magu / 36048 FlyBaseID:FBgn0262169 Length:613 Species:Drosophila melanogaster
Sequence 2:NP_001023098.1 Gene:test-1 / 177010 WormBaseID:WBGene00016918 Length:226 Species:Caenorhabditis elegans


Alignment Length:329 Identity:58/329 - (17%)
Similarity:95/329 - (28%) Gaps:144/329 - (43%)


- Green bases have known domain annotations that are detailed below.


  Fly   154 LASH---QIGYNPDTSASKGSSEAGSTAHRT--CSKSDRSQFNTNLMRMFRNEAQSFFRQPSLSD 213
            ||.|   ...|.......|.|| |....|..  |::|:..:....|::.|::    ...|.|.:|
 Worm     8 LACHVAISAAYISSEDLEKPSS-ADKPVHEKNHCTRSELMRMGGRLVKWFKD----VHAQESGAD 67

  Fly   214 SHILE-----------WQFSKLDTNGNKLLDRQEIRELKKVLRRNVKPRRCGRTFGKYC-DVTKD 266
             |.|:           |.|::.|.|.:..|.:.|:|.:::     .....|...|...| |:..|
 Worm    68 -HTLKLHSVPCRVEVGWMFNQWDGNQDGKLSKAELRPIER-----GGNEACVEEFIDMCDDMVVD 126

  Fly   267 ANLNWLEWSVCFTKEFHNRSAVVNLLASSAATAPPHSTHYSIHNTNVNGHHRGHTNTIGTGVNPH 331
            .:::..||..|||            .:......||  .|.:.|:                 |:||
 Worm   127 GSISVDEWCDCFT------------FSDDLRHEPP--CHKAKHD-----------------VDPH 160

  Fly   332 SYSEDASGSEEHEDNYEDSATGYGGEEDDSQGADLPSSRTHIPSLYMLNSKPETASQDLENDSNC 396
            ...                                                              
 Worm   161 LLG-------------------------------------------------------------- 163

  Fly   397 WMDQSVTLEEQGHGGKSVLFVPQCLPDGRYQRIQCYSSTSTSYCWCVNEDTGKSIPGTSVKNKRP 461
                              :|:|:|..:|.|:..||:...    ||||:. .|:....:.|:|..|
 Worm   164 ------------------VFLPRCDLEGFYKPEQCHDGN----CWCVDR-YGREFDKSRVQNTLP 205

  Fly   462 QCDE 465
            .|.:
 Worm   206 DCGQ 209

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
maguNP_610548.2 KAZAL_FS 38..77 CDD:238052
TY 88..139 CDD:238114
SPARC_Ca_bdg 180..274 CDD:287550 21/107 (20%)
SPARC_EC <219..281 CDD:238155 17/62 (27%)
TY 396..463 CDD:238114 15/66 (23%)
test-1NP_001023098.1 EFh_SPARC_TICN 40..142 CDD:320011 26/123 (21%)
EF-hand motif 77..108 CDD:320011 7/35 (20%)
EF-hand motif 109..140 CDD:320011 10/42 (24%)
TY 149..207 CDD:238114 21/161 (13%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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