DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment magu and Igfbp6

DIOPT Version :9

Sequence 1:	NP_610548.2	Gene:	magu / 36048	FlyBaseID:	FBgn0262169	Length:	613	Species:	Drosophila melanogaster
Sequence 2:	NP_032370.2	Gene:	Igfbp6 / 16012	MGIID:	96441	Length:	238	Species:	Mus musculus

Alignment Length:	240	Identity:	43/240 - (17%)
Similarity:	66/240 - (27%)	Gaps:	108/240 - (45%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 VTW-----------LAVFIATGKSDDQLMKLPACAA------------------------KQGEC 38
            :||           |.:..|.| |...|...|.|.|                        :.|.|
Mouse     1 MTWDGLPTQPLLMLLMLLFAAG-SGSALAGCPGCGAGMQTGCRGGCVEEEDAGSPADGCTEAGGC 64

  Fly    39 DDNEGPVCGT--------------DGQTYPTRCHLL-RAQC----GGHQVSLKYSGSCNACLEAV 84
            ...||..||.              :.:..|.|..|: :.:|    |..:.:.|.|........:.
Mouse    65 LRREGQPCGVYSPKCAPGLQCQPRENEEAPLRALLIGQGRCQRARGPSEETTKESKPQGGASRSR 129

  Fly    85 KFARRQQERDP-----------------------------------------GYFVPRCRKDGNF 108
            ....|.::::|                                         |.:||.|...|.:
Mouse   130 DTNHRDRQKNPRTSAAPIRPNPVQDSEMGPCRRHLDSVLQQLQTEVFRGGARGLYVPNCDLRGFY 194

  Fly   109 AAMQCYGNNG-----CWCSDSQGR--PIADDNKQFRRKGKLRCRA 146
            ...||..:.|     |||.|..|:  |::.|.     :|..:|.|
Mouse   195 RKQQCRSSQGNRRGPCWCVDPMGQPLPVSPDG-----QGSTQCSA 234

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
magu	NP_610548.2	KAZAL_FS	38..77	CDD:238052	12/57 (21%)
		TY	88..139	CDD:238114	17/98 (17%)
		SPARC_Ca_bdg	180..274	CDD:287550
		SPARC_EC	<219..281	CDD:238155
		TY	396..463	CDD:238114
Igfbp6	NP_032370.2	IB	28..106	CDD:197525	12/77 (16%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	104..159		6/54 (11%)
		Thyroglobulin_1	160..232	CDD:278514	16/76 (21%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	218..238		5/22 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000