DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment magu and Igfbp1

DIOPT Version :9

Sequence 1:	NP_610548.2	Gene:	magu / 36048	FlyBaseID:	FBgn0262169	Length:	613	Species:	Drosophila melanogaster
Sequence 2:	NP_032367.3	Gene:	Igfbp1 / 16006	MGIID:	96436	Length:	272	Species:	Mus musculus

Alignment Length:	175	Identity:	43/175 - (24%)
Similarity:	61/175 - (34%)	Gaps:	34/175 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   320 HTNTIGTGV---NPHSYSEDASGSEEHE---------DNYEDSATGYGGEEDDSQGAD----LPS 368
            |..|.|.|.   .|.:.:.....|.:||         |...:|.     |..:.|..|    :..
Mouse    97 HALTRGQGACVPEPAAPATSTLFSSQHEEAKAAVVSADELSESP-----EMTEEQLLDSFHLMAP 156

  Fly   369 SRTHIPSLY----MLNSKPETASQDLEN-DSNCWMDQSVTLEE----QGHGGKSV--LFVPQCLP 422
            ||...|.|:    ..:|.......||:. ...|..:....||.    |...|..:  .::|.|..
Mouse   157 SREDQPILWNAISTYSSMRAREIADLKKWKEPCQRELYKVLERLAAAQQKAGDEIYKFYLPNCNK 221

  Fly   423 DGRYQRIQCYSST--STSYCWCVNEDTGKSIPGTSVKNKRPQCDE 465
            :|.|...||.:|.  ....||||...:||.|||:......|.|.:
Mouse   222 NGFYHSKQCETSLDGEAGLCWCVYPWSGKKIPGSLETRGDPNCHQ 266

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
magu	NP_610548.2	KAZAL_FS	38..77	CDD:238052
		TY	88..139	CDD:238114
		SPARC_Ca_bdg	180..274	CDD:287550
		SPARC_EC	<219..281	CDD:238155
		TY	396..463	CDD:238114	22/74 (30%)
Igfbp1	NP_032367.3	IB	30..107	CDD:197525	4/9 (44%)
		Thyroglobulin_1	189..264	CDD:278514	22/74 (30%)
		Cell attachment site	259..261		0/1 (0%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000