DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment magu and Sparcl1

DIOPT Version :9

Sequence 1:	NP_610548.2	Gene:	magu / 36048	FlyBaseID:	FBgn0262169	Length:	613	Species:	Drosophila melanogaster
Sequence 2:	NP_001345943.1	Gene:	Sparcl1 / 13602	MGIID:	108110	Length:	650	Species:	Mus musculus

Alignment Length:	278	Identity:	68/278 - (24%)
Similarity:	96/278 - (34%)	Gaps:	90/278 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 KSDDQLMKLPACAAKQGECDDNE--------GPVCGTDGQTYPTRCHLLRAQC------GGHQVS 70
            |:|.|  ..|.|.     |.|.|        ...||||.|||.:.|||...:|      .|||:.
Mouse   431 KTDPQ--GKPHCV-----CQDPETCPPAKILDQACGTDNQTYASSCHLFATKCRLEGTKKGHQLQ 488

  Fly    71 LKYSGSCNACLEAVKFARRQQERDPGYFVPRCRKDGNFAAMQCYGNN---GCWCSDSQGRPIADD 132
            |.|.|:|.:......|...|       |..|.|.......||.|..|   |.:.::.|
Mouse   489 LDYFGACKSIPACTDFEVAQ-------FPLRMRDWLKNILMQLYEPNPKHGGYLNEKQ------- 539

  Fly   133 NKQFRRKGKLRCRANRRDRRRLA-SHQIGYNPDTSASKGSSEAGSTAHRTCSKSDRSQFNTNLMR 196
                |.|.|   :....::|.|| .|.|..                                |:|
Mouse   540 ----RSKVK---KIYLDEKRLLAGDHPIEL--------------------------------LLR 565

  Fly   197 MFRNEAQSFFRQPSLSDSHILEWQFSKLDTN-GNKLLDRQEIRELKKVLRRNVKPRRCGRTFGKY 260
            .|:.....:.        :.:.|||::||.: .:::|...|:..|:..|   |....|...|.:.
Mouse   566 DFKKNYHMYV--------YPVHWQFNELDQHPADRILTHSELAPLRASL---VPMEHCITRFFEE 619

  Fly   261 CDVTKDANLNWLEWSVCF 278
            ||..||.::...||..||
Mouse   620 CDPNKDKHITLKEWGHCF 637

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
magu	NP_610548.2	KAZAL_FS	38..77	CDD:238052	20/52 (38%)
		TY	88..139	CDD:238114	11/53 (21%)
		SPARC_Ca_bdg	180..274	CDD:287550	19/94 (20%)
		SPARC_EC	<219..281	CDD:238155	20/61 (33%)
		TY	396..463	CDD:238114
Sparcl1	NP_001345943.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	51..352
		MDN1	<60..317	CDD:227596
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	375..415
		KAZAL_FS	419..498	CDD:412159	26/73 (36%)
		EFh_SPARC_like	501..641	CDD:320010	42/201 (21%)
		EF-hand motif	574..606	CDD:320010	8/39 (21%)
		EF-hand motif	609..639	CDD:320010	10/29 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910