DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment magu and AgaP_AGAP003400

DIOPT Version :9

Sequence 1:	NP_610548.2	Gene:	magu / 36048	FlyBaseID:	FBgn0262169	Length:	613	Species:	Drosophila melanogaster
Sequence 2:	XP_311685.5	Gene:	AgaP_AGAP003400 / 1272775	VectorBaseID:	AGAP003400	Length:	545	Species:	Anopheles gambiae

Alignment Length:	372	Identity:	87/372 - (23%)
Similarity:	142/372 - (38%)	Gaps:	93/372 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 VCGTDGQTYPTRCHLLRAQCGGHQVSLKYS--GSCNACLEAVKFARRQQERDPGYFVPRCRKDGN 107
            :||:|..||.:.|.|....| .|...:|.:  |.| .| :..::.::||::       :.:::.|
Mosquito   196 LCGSDNWTYSSLCRLEYHNC-IHTTEVKVNCMGFC-PC-KGKRWQQQQQQQ-------QLKEEKN 250

  Fly   108 FAAMQCYGNNGCWCSDSQ----GRPIADDNKQFR------RKGKL---------RCRANRRDRRR 153
                :.|.:     .:||    ...|..|||.::      .|||.         ..|....|:.:
Mosquito   251 ----RHYNH-----INSQYTFTPEEIKYDNKHYKYIKYTTYKGKYDGYGSSGSGSTRMTGEDKHK 306

  Fly   154 LASHQIGYN------PDTSASKGSSE----AGSTAHRTCSKSDRSQFNTNLMRMF---------R 199
            :.    |||      ..||.:.|:|:    :||:|...|.....:.....|:..|         |
Mosquito   307 IR----GYNEVLDKPASTSNNNGNSKPSKLSGSSARNECKPQQLTAIGNRLLDWFSVIMADSKKR 367

  Fly   200 NEAQSFFRQPSLSDSHILE--WQFSKLDTNGNKLLDRQEIRELKKVLRRNVKPRRCGRTFGKYCD 262
            .:.|....:.....:..||  |.|..||.|.:..|..||:.:|:     :.:..||.:.|...||
Mosquito   368 RQHQQQKNKVHFPAACKLEARWMFGHLDLNNDGELSTQELYDLE-----HDQNERCIKPFIDTCD 427

  Fly   263 VTKDANLNWLEWSVCFTKEFHNRSAVVNLLAS--SAATAP---------PHSTHYSI-------- 308
            :.:|..::..||..||.|.....:||...|.:  |.:.||         |...|.::
Mosquito   428 LDQDNTIDPREWCRCFEKTDRPCAAVRRRLGNDLSGSYAPDCDSQGFYKPTQCHQAVGVCWCVDE 492

  Fly   309 HNTN-VNGHHRGHTN---TIGTGVNPHSYSEDASGSEEHEDNYEDSA 351
            |... .|...||..|   .|......:|..||...|::.:|:.|.||
Mosquito   493 HGVEFANTRTRGKPNCEEIINNATTLNSDDEDTEDSDDDDDSQEGSA 539

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
magu	NP_610548.2	KAZAL_FS	38..77	CDD:238052	11/33 (33%)
		TY	88..139	CDD:238114	10/60 (17%)
		SPARC_Ca_bdg	180..274	CDD:287550	22/104 (21%)
		SPARC_EC	<219..281	CDD:238155	19/61 (31%)
		TY	396..463	CDD:238114
AgaP_AGAP003400	XP_311685.5	KAZAL	<197..229	CDD:197624	11/32 (34%)
		SPARC_EC	340..453	CDD:238155	27/117 (23%)
		SPARC_Ca_bdg	340..440	CDD:287550	23/104 (22%)
		TY	449..508	CDD:238114	12/58 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910