DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment magu and SPINK5

DIOPT Version :9

Sequence 1:	NP_610548.2	Gene:	magu / 36048	FlyBaseID:	FBgn0262169	Length:	613	Species:	Drosophila melanogaster
Sequence 2:	NP_001121170.1	Gene:	SPINK5 / 11005	HGNCID:	15464	Length:	1094	Species:	Homo sapiens

Alignment Length:	137	Identity:	39/137 - (28%)
Similarity:	53/137 - (38%)	Gaps:	41/137 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 KQGE------CDDNEGPVCGTDGQTYPTRCHLLRAQCG-----GHQVSLKYSGSC-------NAC 80
            |:||      |.|....||||||:||..||    |.|.     |.|:.:|..|.|       :.|
Human   101 KKGERDGDFICPDYYEAVCGTDGKTYDNRC----ALCAENAKTGSQIGVKSEGECKSSNPEQDVC 161

  Fly    81 LEAVKFARR-----QQERDPGYFVPRCRKDGNFAAMQCYGNNGCWCSDSQGRPIADDNKQFRRKG 140
            .....|.|.     .:|.|| ...|..:..||..||         |::.    ...:.:..:|:|
Human   162 SAFRPFVRDGRLGCTRENDP-VLGPDGKTHGNKCAM---------CAEL----FLKEAENAKREG 212

  Fly   141 KLRCRAN 147
            :.|.|.|
Human   213 ETRIRRN 219

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
magu	NP_610548.2	KAZAL_FS	38..77	CDD:238052	18/43 (42%)
		TY	88..139	CDD:238114	10/55 (18%)
		SPARC_Ca_bdg	180..274	CDD:287550
		SPARC_EC	<219..281	CDD:238155
		TY	396..463	CDD:238114
SPINK5	NP_001121170.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910