DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment magu and sparcl2

DIOPT Version :9

Sequence 1:	NP_610548.2	Gene:	magu / 36048	FlyBaseID:	FBgn0262169	Length:	613	Species:	Drosophila melanogaster
Sequence 2:	XP_017207307.1	Gene:	sparcl2 / 100534809	ZFINID:	ZDB-GENE-131127-575	Length:	259	Species:	Danio rerio

Alignment Length:	217	Identity:	56/217 - (25%)
Similarity:	85/217 - (39%)	Gaps:	48/217 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   422 PDGRYQRIQCYSSTSTSYCWCVNED---TGKSI-PGTSVKNKRPQCD------------ESVAVR 470
            |:...|.::|:|... |:|..|.|:   |.|.: |.|..:.:.|.|.            ...|.|
Zfish    44 PESLCQLLKCHSPIG-SWCQVVKEEGVLTPKCVCPSTCPRQRAPVCSVLGKTYSNECLLHKEACR 107

  Fly   471 PMK---------------GCTEPRKTQFLKELKAYLNTSLLPS-------STTGSNSSMWKTDDE 513
            ..:               ||:|....||...|   |:..||.|       ....|.|.:..|...
Zfish   108 KERRIGKAHNGACLVSETGCSEEEFGQFPYRL---LDWFLLLSRMGERYTPAAPSQSCLSHTQRM 169

  Fly   514 RIATLSFVYLDKNKNKSWDRREWKNFRDLVTSASHLRRCGKKMPRYCDVNGDKKISLAEWLNCLQ 578
            ::|...||.||:|::....||:   .|.|......|..|.::..:.||.|.:||::|.||.:||
Zfish   170 QLAQRRFVLLDRNRDGKLSRRD---LRKLHYKRMPLEHCAQRFFQSCDKNQNKKVTLREWTSCL- 230

  Fly   579 ATPRESATTAKPAQSNETASPK 600
              .:.|....:...|.:..|||
Zfish   231 --VKRSERWFEDFMSMKMGSPK 250

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
magu	NP_610548.2	KAZAL_FS	38..77	CDD:238052
		TY	88..139	CDD:238114
		SPARC_Ca_bdg	180..274	CDD:287550
		SPARC_EC	<219..281	CDD:238155
		TY	396..463	CDD:238114	13/44 (30%)
sparcl2	XP_017207307.1	KAZAL	75..120	CDD:197624	6/44 (14%)
		SPARC_EC	127..232	CDD:238155	34/113 (30%)
		SPARC_Ca_bdg	127..226	CDD:287550	30/104 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910