DRSC/TRiP Functional Genomics Resources

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Protein Alignment sel and CNPY2

DIOPT Version :10

Sequence 1:NP_610547.1 Gene:sel / 36046 FlyBaseID:FBgn0263260 Length:189 Species:Drosophila melanogaster
Sequence 2:NP_055070.1 Gene:CNPY2 / 10330 HGNCID:13529 Length:182 Species:Homo sapiens


Alignment Length:174 Identity:52/174 - (29%)
Similarity:98/174 - (56%) Gaps:10/174 - (5%)


- Green bases have known domain annotations that are detailed below.


  Fly     5 ALILFGLLALAQGYSFTSREVKCHVCKAVVTELEEAIAKEDPHKMADVSGFRLDAQGNSISKKVR 69
            ||:|..||..|  ::..|:::.|..|:|:|.|||..||:.||.|...:..||::..|:....:|.
Human     8 ALLLGALLGTA--WARRSQDLHCGACRALVDELEWEIAQVDPKKTIQMGSFRINPDGSQSVVEVP 70

  Fly    70 LVKSEMFLTELMEKICEKMDDYLKATYKSNGKFTLLKMIINGQMNPDSSLVDFVQ---DGDLNKS 131
            ..:||..||||:|:||::|.:|.:....|..:...::::  |: |.:||.:|...   |.|::.:
Human    71 YARSEAHLTELLEEICDRMKEYGEQIDPSTHRKNYVRVV--GR-NGESSELDLQGIRIDSDISGT 132

  Fly   132 LGHFCNEVLEDNDEIFVKAFQAEELGNDLDIKICSEQASYCDES 175
            |...|..::|:.::..::.|..|  .:::..|:||::...||.:
Human   133 LKFACESIVEEYEDELIEFFSRE--ADNVKDKLCSKRTDLCDHA 174

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
selNP_610547.1 DUF3456 26..172 CDD:463404 43/148 (29%)
CNPY2NP_055070.1 DUF3456 27..171 CDD:463404 43/148 (29%)
Prevents secretion from ER. /evidence=ECO:0000255|PROSITE-ProRule:PRU10138 179..182
Blue background indicates that the domain is not in the aligned region.

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