DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment oys and Mboat2

DIOPT Version :9

Sequence 1:	NP_001286265.1	Gene:	oys / 36045	FlyBaseID:	FBgn0033476	Length:	722	Species:	Drosophila melanogaster
Sequence 2:	NP_080313.2	Gene:	Mboat2 / 67216	MGIID:	1914466	Length:	519	Species:	Mus musculus

Alignment Length:	517	Identity:	209/517 - (40%)
Similarity:	292/517 - (56%)	Gaps:	23/517 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 GSRTFTWLADMVGLSVDLVNFLICQISALFLASLFRSMLHPSKVSSKLRHTFALSIGLAFGYFCF 79
            ||.....|::.|.|.:|.|||::||:.||..|..||:.||.||.||.:||..|..:||...:|||
Mouse     8 GSTLLQPLSNAVQLPIDQVNFVVCQLFALLAAVWFRTYLHSSKTSSFIRHVVATLLGLYLAFFCF 72

  Fly    80 GQQAIHIAGLPAICYIVIRTQDPRIVQRAVLLVAMSYLLCVHLMR-QLYDYGSYALDITGPLMII 143
            |..|:|......|.|.::.......:|:...:.|:.||....:.| .::|||.|:.|.:||:|||
Mouse    73 GWYALHFLVQSGISYCIMIIAGVESMQQCCFVFALGYLSVCQITRVYIFDYGQYSADFSGPMMII 137

  Fly   144 TQKVTSLAFSIHDGFVRGDEELTKAQQYHAIRKMPSALEYFSYVWHFQSILAGPLVFYKDYIEFV 208
            |||:||||:.||||..|.|||||.:|:..|:|:|||.|||.||..:|..||||||..|||||.|:
Mouse   138 TQKITSLAYEIHDGMFRKDEELTPSQRGLAVRRMPSLLEYVSYTCNFMGILAGPLCSYKDYIAFI 202

  Fly   209 EG-YNLLSTPPGNGNLDSSKREVVLEPSPTKAVIRKVVGSLVCAFIFMKFVKI---YPVKDMKED 269
            || .:.::.|..||   ..::....:|||..||..|:   |||....:..:.|   .||:...::
Mouse   203 EGRASHVAQPSENG---KDEQHGKADPSPNAAVTEKL---LVCGLSLLFHLTISNMLPVEYNIDE 261

  Fly   270 DFMNNTSMVYKYWYAMMATTCIRFKYYHAWLLADAICNNSGLGFTGYDKDGNSKWDLISNINVLS 334
            .|....|...|..|..::....|.|||.||.|||||.|.:|.||.||||:|.::||||||:.:..
Mouse   262 HFQATASWPTKATYLYVSLLAARPKYYFAWTLADAINNAAGFGFRGYDKNGVARWDLISNLRIQQ 326

  Fly   335 FEFSTNMRDAINNWNCGTNRWLRTLVYERV---PQQYGTLLTFALSAVWHGFYPGYYLTFATGAV 396
            .|.||:.:..::|||..|..||:.:.|||.   |    |:.||.|||:|||.||||||||.||.:
Mouse   327 IEMSTSFKMFLDNWNIQTALWLKRVCYERATFSP----TIQTFFLSAIWHGVYPGYYLTFLTGVL 387

  Fly   397 VVTAARTGRRLFRHRFQSTQVTRMFYDILTCLITRVVLGYATFPFVLLEFMGSIKLYLRFYLCLH 461
            :..|||..|..|||.|......::|||::|.:.|::.:.|...|||||....|...|..:|.|||
Mouse   388 MTLAARAVRNNFRHYFLEPPQLKLFYDLITWVATQITISYTVVPFVLLSIKPSFTFYSSWYYCLH 452

  Fly   462 IISLVTIFILPKFIRGERRLRTSNGNGNVRLSGSGNTKDAVTTSVESTAALTAGNDLNEDKE 523
            :.|::.:.:|| ..:.:||..|..   ||.|| .....|.....:...:..|..|..|::::
Mouse   453 VCSILVLLLLP-VKKSQRRTSTQE---NVHLS-QAKKFDERDNPLGQNSFSTMNNVCNQNRD 509

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
oys	NP_001286265.1	MBOAT	22..484	CDD:294479	198/469 (42%)
Mboat2	NP_080313.2	MBOAT	13..476	CDD:294479	199/476 (42%)
Mboat2	NP_080313.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	497..519		3/13 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167835171
Domainoid	1	1.000	267	1.000	Domainoid score	I1853
eggNOG	1	0.900	-	-		E1_COG5202
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6971
Inparanoid	1	1.050	370	1.000	Inparanoid score	I2113
Isobase	1	0.950	-	0	Normalized mean entropy	S2296
OMA	1	1.010	-	-		QHG54526
OrthoDB	1	1.010	-	-		D881262at2759
OrthoFinder	1	1.000	-	-		FOG0001502
OrthoInspector	1	1.000	-	-		otm43840
orthoMCL	1	0.900	-	-		OOG6_101140
Panther	1	1.100	-	-	LDO	PTHR13906
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3130
SonicParanoid	1	1.000	-	-		X1230
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	17	16.750