DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment oys and Mboat1

DIOPT Version :9

Sequence 1:	NP_001286265.1	Gene:	oys / 36045	FlyBaseID:	FBgn0033476	Length:	722	Species:	Drosophila melanogaster
Sequence 2:	NP_001102590.1	Gene:	Mboat1 / 498741	RGDID:	1565561	Length:	492	Species:	Rattus norvegicus

Alignment Length:	482	Identity:	194/482 - (40%)
Similarity:	284/482 - (58%)	Gaps:	13/482 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 GSRTFTWLADMVGLSVDLVNFLICQISALFLASLFRSMLHPSKVSSKLRHTFALSIGLAFGYFCF 79
            ||.....|:.::|:.:|.|||:.||:.||..|..||..|.|.|.|.::|||.|..:|:.|..|||
  Rat    15 GSTCLHPLSQLLGIPLDQVNFVACQLLALSAAFWFRIYLRPGKASPEVRHTLATILGIYFVVFCF 79

  Fly    80 GQQAIHIAGLPAICYIVIRTQDPRIVQRAVLLVAMSYLLCVHLMR-QLYDYGSYALDITGPLMII 143
            |..|:|:..|..:||.|:.|.....:.|....|||.||...|:.| .::.||....|.:|||||:
  Rat    80 GWYAVHLFVLVLMCYGVMVTASVSNIHRYSFFVAMGYLTICHISRIYIFHYGILTTDFSGPLMIV 144

  Fly   144 TQKVTSLAFSIHDGFVRGDEELTKAQQYHAIRKMPSALEYFSYVWHFQSILAGPLVFYKDYIEFV 208
            |||:|:|||.:|||..|..|:|:..|...|::..||.|||.||..:|.|::|||...:|||:.|:
  Rat   145 TQKITTLAFQVHDGLGRKAEDLSAEQHRLAVKVKPSLLEYLSYHLNFMSVIAGPCNNFKDYVAFI 209

  Fly   209 EG----YNLLSTPPGNGNLDSSKREVVLEPSPTKAVIRKVVGSLVCAFIFMKFVKIYPVKDMKED 269
            ||    ..||..     |......:.:.|||||.|||:|:..:|:...:|:...|.:||..:.:|
  Rat   210 EGRHIHMKLLEV-----NWKERGFQSLPEPSPTGAVIQKLCITLMSLLLFLTLSKSFPVTFLIDD 269

  Fly   270 DFMNNTSMVYKYWYAMMATTCIRFKYYHAWLLADAICNNSGLGFTGYDKDGNSKWDLISNINVLS 334
            .|::..:.:.:.||..:.....:.|||.||.||||:.|.:|.||:|.|.||||.|||:||:|:..
  Rat   270 WFVHKANFLSRLWYLYVVMQAAKPKYYFAWTLADAVHNAAGFGFSGIDADGNSCWDLLSNLNIWK 334

  Fly   335 FEFSTNMRDAINNWNCGTNRWLRTLVYERVPQQYGTLLTFALSAVWHGFYPGYYLTFATGAVVVT 399
            .|.:|:.:..:.|||..|:.||:.:.||||| .|.|:|||.|||:|||.|||||.||.||..|..
  Rat   335 IETATSFKMYLENWNIQTSTWLKCVCYERVP-WYPTVLTFLLSALWHGVYPGYYFTFLTGVPVTL 398

  Fly   400 AARTGRRLFRHRFQSTQVTRMFYDILTCLITRVVLGYATFPFVLLEFMGSIKLYLRFYLCLHIIS 464
            |||..|..:||.|.:::..::.||::|..:|::.:.|...|||:|....:|.||...:..|||:.
  Rat   399 AARAVRNNYRHHFLASKARKVAYDVVTWAVTQLAVSYTAAPFVMLAVEPTISLYKSMFFFLHILC 463

  Fly   465 LVTIFILPKFIRGERRLRTSNGNGNVR 491
            |:.|.:||  ::..:..|.|....:|:
  Rat   464 LLIILLLP--VKPRQPQRQSQSPNSVK 488

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
oys	NP_001286265.1	MBOAT	22..484	CDD:294479	190/466 (41%)
Mboat1	NP_001102590.1	MBOAT	21..458	CDD:294479	182/442 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166338771
Domainoid	1	1.000	267	1.000	Domainoid score	I1800
eggNOG	1	0.900	-	-		E1_COG5202
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	367	1.000	Inparanoid score	I2085
OMA	1	1.010	-	-		QHG54526
OrthoDB	1	1.010	-	-		D881262at2759
OrthoFinder	1	1.000	-	-		FOG0001502
OrthoInspector	1	1.000	-	-		otm45926
orthoMCL	1	0.900	-	-		OOG6_101140
Panther	1	1.100	-	-	O	PTHR13906
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1230
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	14	13.810