DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment oys and Lpcat3

DIOPT Version :9

Sequence 1:	NP_001286265.1	Gene:	oys / 36045	FlyBaseID:	FBgn0033476	Length:	722	Species:	Drosophila melanogaster
Sequence 2:	NP_001012189.1	Gene:	Lpcat3 / 362434	RGDID:	1310223	Length:	487	Species:	Rattus norvegicus

Alignment Length:	469	Identity:	116/469 - (24%)
Similarity:	201/469 - (42%)	Gaps:	47/469 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 LADMVGLSVDLVNFLICQISALFLASLFRSMLHPSKVSSKLRHTFALSIGLAFGYFCFGQQAIHI 86
            ||..:|.|...:..:........||..:|..|...  .|.|.|.|....||:..||.||.|..|
  Rat    31 LATSLGASEQALRLIFSIFLGYPLALFYRHYLFYK--DSYLIHLFHAFSGLSIAYFNFGHQFYH- 92

  Fly    87 AGLPAICYIVIRTQDPRIVQRAVLLVAMSYLLCVHLMRQLYDY-----GSYALDITGPLMIITQK 146
                ::..:|::....|::.|.:  .|:...||..:...|..|     |.|.:..|.|..::|.|
  Rat    93 ----SLLCVVLQFLILRLMGRTI--TAVFTTLCFQMAYLLAGYYYTATGDYDIKWTMPHCVLTLK 151

  Fly   147 VTSLAFSIHDGFVRGDEELTKAQQYHAIRKMPSALEYFSYVWHFQSILAGPLVFYKDYIEFVEGY 211
            :..|:...:|| .:....|:..||.:||..:||.||...:.:.:.:.|.||......|::.|:|.
  Rat   152 LIGLSIDYYDG-GKDRNSLSSEQQKYAILGVPSLLEVAGFSYFYGAFLVGPQFSMNHYMKLVKGQ 215

  Fly   212 NLLSTPPGNGNLDSSKREVVLEPSPTKAVIRKVVGSLVCAFIFMKFVKIYPVKDMKEDDFMNNTS 276
              |:..||.            .|:.|...::::...||   ..:.:..:.|  .:.||..:....
  Rat   216 --LTDVPGK------------MPNSTIPALKRLSLGLV---YLVGYTLLSP--HITEDYLLTEDY 261

  Fly   277 MVYKYW----YAMMATTCIRFKYYHAWLLADAICNNSGLGFTGYDKDGNSKWDLISNINVLSFEF 337
            ....:|    |.::....:.:||...||:.:.:|..|||||.|::::|..|||..:|:.|..||.
  Rat   262 DTRPFWFRCMYMLIWGKFVLYKYVTCWLVTEGVCILSGLGFNGFEENGTVKWDACANMKVWLFET 326

  Fly   338 STNMRDAINNWNCGTNRWLRTLVYERVP----QQYGTLLTFALSAVWHGFYPGYYLTFATGAVVV 398
            :......|.::|..||.|:...:::|:.    ::....|:....|:|||.:.||.:.|....::|
  Rat   327 TPRFTGTIASFNINTNAWVARYIFKRLKFLGNKELSQGLSLLFLALWHGLHSGYLICFQMEFLIV 391

  Fly   399 TAARTGRRLFR-----HRFQSTQVTRMFYDILTCLITRVVLGYATFPFVLLEFMGSIKLYLRFYL 458
            ...:....|.|     ....|....:.||.::...|..:.:||:...|.|..:...:|:|...|.
  Rat   392 IVEKQATNLIRDSPALSSLASITALQPFYYLVQQTIHWLFMGYSMTAFCLFTWDKWLKVYRSIYF 456

  Fly   459 CLHIISLVTIFILP 472
            ..|:..|..:|.||
  Rat   457 LGHVFFLSLLFTLP 470

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
oys	NP_001286265.1	MBOAT	22..484	CDD:294479	116/469 (25%)
Lpcat3	NP_001012189.1	MBOAT	126..437	CDD:281107	80/330 (24%)
Lpcat3	NP_001012189.1	Di-lysine motif	484..487
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5202
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54526
OrthoDB	1	1.010	-	-		D881262at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.830