DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment oys and MBOAT1

DIOPT Version :9

Sequence 1:	NP_001286265.1	Gene:	oys / 36045	FlyBaseID:	FBgn0033476	Length:	722	Species:	Drosophila melanogaster
Sequence 2:	NP_001073949.1	Gene:	MBOAT1 / 154141	HGNCID:	21579	Length:	495	Species:	Homo sapiens

Alignment Length:	478	Identity:	198/478 - (41%)
Similarity:	277/478 - (57%)	Gaps:	13/478 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 GSRTFTWLADMVGLSVDLVNFLICQISALFLASLFRSMLHPSKVSSKLRHTFALSIGLAFGYFCF 79
            ||.....|::::|:.:|.|||::||:.|||.|..||..|.|...||.:||..|...|:.|..|||
Human    16 GSTYLHPLSELLGIPLDQVNFVVCQLVALFAAFWFRIYLRPGTTSSDVRHAVATIFGIYFVIFCF 80

  Fly    80 GQQAIHIAGLPAICYIVIRTQDPRIVQRAVLLVAMSYLLCVHLMR-QLYDYGSYALDITGPLMII 143
            |..::|:..|..:||.::.|.....:.|....|||.||...|:.| .::.||....|.:|||||:
Human    81 GWYSVHLFVLVLMCYAIMVTASVSNIHRYSFFVAMGYLTICHISRIYIFHYGILTTDFSGPLMIV 145

  Fly   144 TQKVTSLAFSIHDGFVRGDEELTKAQQYHAIRKMPSALEYFSYVWHFQSILAGPLVFYKDYIEFV 208
            |||:|:|||.:|||..|..|:|:..|...||:..||.|||.||:.:|.|::|||...:||||.|:
Human   146 TQKITTLAFQVHDGLGRRAEDLSAEQHRLAIKVKPSFLEYLSYLLNFMSVIAGPCNNFKDYIAFI 210

  Fly   209 EG----YNLLSTPPGNGNLDSSKREVVLEPSPTKAVIRKVVGSLVCAFIFMKFVKIYPVKDMKED 269
            ||    ..||..     |........:.|||||.|||.|:..:||...:|:...|.:||..:.:|
Human   211 EGKHIHMKLLEV-----NWKRKGFHSLPEPSPTGAVIHKLGITLVSLLLFLTLTKTFPVTCLVDD 270

  Fly   270 DFMNNTSMVYKYWYAMMATTCIRFKYYHAWLLADAICNNSGLGFTGYDKDGNSKWDLISNINVLS 334
            .|::..|...:..|..:.....:.|||.||.||||:.|.:|.||:|.||:||..|||:||:|:..
Human   271 WFVHKASFPARLCYLYVVMQASKPKYYFAWTLADAVNNAAGFGFSGVDKNGNFCWDLLSNLNIWK 335

  Fly   335 FEFSTNMRDAINNWNCGTNRWLRTLVYERVPQQYGTLLTFALSAVWHGFYPGYYLTFATGAVVVT 399
            .|.:|:.:..:.|||..|..||:.:.|:||| .|.|:|||.|||:|||.|||||.||.||.:|..
Human   336 IETATSFKMYLENWNIQTATWLKCVCYQRVP-WYPTVLTFILSALWHGVYPGYYFTFLTGILVTL 399

  Fly   400 AARTGRRLFRHRFQSTQVTRMFYDILTCLITRVVLGYATFPFVLLEFMGSIKLYLRFYLCLHIIS 464
            |||..|..:||.|.|::..:..||..|..:|::.:.|...|||:|....:|.||...|..|||||
Human   400 AARAVRNNYRHYFLSSRALKAVYDAGTWAVTQLAVSYTVAPFVMLAVEPTISLYKSMYFYLHIIS 464

  Fly   465 LVTIFILPKFIRG--ERRLRTSN 485
            |:.|..||...:.  :||.:|.|
Human   465 LLIILFLPMKPQAHTQRRPQTLN 487

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
oys	NP_001286265.1	MBOAT	22..484	CDD:294479	194/468 (41%)
MBOAT1	NP_001073949.1	MBOAT	22..458	CDD:294479	182/441 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145062
Domainoid	1	1.000	272	1.000	Domainoid score	I1811
eggNOG	1	0.900	-	-		E1_COG5202
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	376	1.000	Inparanoid score	I2097
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54526
OrthoDB	1	1.010	-	-		D881262at2759
OrthoFinder	1	1.000	-	-		FOG0001502
OrthoInspector	1	1.000	-	-		otm41788
orthoMCL	1	0.900	-	-		OOG6_101140
Panther	1	1.100	-	-	O	PTHR13906
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3130
SonicParanoid	1	1.000	-	-		X1230
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	15	14.800