DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1407 and PFA3

DIOPT Version :9

Sequence 1:	NP_001286264.1	Gene:	CG1407 / 36043	FlyBaseID:	FBgn0033474	Length:	452	Species:	Drosophila melanogaster
Sequence 2:	NP_014073.1	Gene:	PFA3 / 855390	SGDID:	S000005270	Length:	336	Species:	Saccharomyces cerevisiae

Alignment Length:	295	Identity:	80/295 - (27%)
Similarity:	135/295 - (45%)	Gaps:	51/295 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 PVLFITAVIAWSYYAYVVELCIRNSENRIGMIFMLLFYHLFLTLFMWSYWRTIMTSVGRIPDQWR 88
            |....|.:..|:.|..:..:      ::|...|:.|.....|.:.:::|::.|....|...|
Yeast    12 PRCLTTCLYIWTAYITLTRI------HQIPRWFLALTIVPTLAVALYTYYKVIARGPGSPLD--- 67

  Fly    89 IPDEEVSRLFRADSPDTQKRILNNFARDLP---VTNRTM----NGSVRFCEKCKIIKPDRAHHCS 146
            .||..|..|..|::           ..:||   ::.|.:    :|..|.|:.|.:.||||.||||
Yeast    68 FPDLLVHDLKAAEN-----------GLELPPEYMSKRCLTLKHDGRFRVCQVCHVWKPDRCHHCS 121

  Fly   147 VCSCCVLKMDHHCPWVNNCVNFYNYKYFVLFLGYALVYCLYVAFTSLHDFVEFWKVGAYDNNGYS 211
            .|..|:|||||||||...|..|.|.|:|:.||.|..:|...|...:.::      :|.:.|:|..
Yeast   122 SCDVCILKMDHHCPWFAECTGFRNQKFFIQFLMYTTLYAFLVLIYTCYE------LGTWFNSGSF 180

  Fly   212 AQGQLNASGMGRFHILFLFFIAIMFAISLVSLFGYHIYLVLVNRTTLE-----SFRAPI------ 265
            .:..::      ||:|.:..:|:...||:::...:.||.|..|:||:|     .:|..:
Yeast   181 NRELID------FHLLGVALLAVAVFISVLAFTCFSIYQVCKNQTTIEVHGMRRYRRDLEILNDS 239

  Fly   266 FRVGGPDKNGYNLG-RYANFCEVFGDDWQYWFLPV 299
            :......:|.::|| ..||:.::.|..|..|.||:
Yeast   240 YGTNEHLENIFDLGSSMANWQDIMGTSWLEWILPI 274

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1407	NP_001286264.1	zf-DHHC	129..259	CDD:279823	47/129 (36%)
PFA3	NP_014073.1	COG5273	1..304	CDD:227598	80/295 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	102	1.000	Domainoid score	I1524
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	112	1.000	Inparanoid score	I1366
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000300
OrthoInspector	1	1.000	-	-		otm46542
orthoMCL	1	0.900	-	-		OOG6_100499
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1716
SonicParanoid	1	1.000	-	-		X260
TreeFam	1	0.960	-	-
	11	10.750