DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1407 and zdhhc15b

DIOPT Version :9

Sequence 1:	NP_001286264.1	Gene:	CG1407 / 36043	FlyBaseID:	FBgn0033474	Length:	452	Species:	Drosophila melanogaster
Sequence 2:	NP_001071249.1	Gene:	zdhhc15b / 777734	ZFINID:	ZDB-GENE-061110-106	Length:	332	Species:	Danio rerio

Alignment Length:	295	Identity:	138/295 - (46%)
Similarity:	199/295 - (67%)	Gaps:	14/295 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 CMAVFKWIPVLFITAVIAWSYYAYVVELCIRNSENRIGMIFMLLFYHLFLTLFMWSYWRTIMTSV 80
            |..:|.||||:.|::|:.|||||||.|||.....|.:|.:..||.:|:...:|.|:||:.|.|..
Zfish    10 CQRIFSWIPVIIISSVVLWSYYAYVFELCFVTLSNNLGRVTYLLIFHVCFIMFCWTYWKAIFTPP 74

  Fly    81 GRIPDQWRIPDEEVSRLFRADSPDTQKRILNNFARDLPVTNRTMNGSVRFCEKCKIIKPDRAHHC 145
            .....::.:...:..|....:.|:.||:||.:.|:.||:..|..:|::|||::|::|||||.|||
Zfish    75 STPTKKFHLSYTDKERYEMEERPEVQKQILVDIAKKLPIFTRAQSGAIRFCDRCQVIKPDRCHHC 139

  Fly   146 SVCSCCVLKMDHHCPWVNNCVNFYNYKYFVLFLGYALVYCLYVAFTSLHDFVEFWKVGAYDNNGY 210
            |||..||||||||||||||||.|.|||:|:|||.|:::||:::|.|....|::|| ||...|
Zfish   140 SVCETCVLKMDHHCPWVNNCVGFSNYKFFLLFLSYSMIYCVFIASTVFQYFLKFW-VGDLPN--- 200

  Fly   211 SAQGQLNASGMGRFHILFLFFIAIMFAISLVSLFGYHIYLVLVNRTTLESFRAPIFRVGGPDKNG 275
                     |..:||:|||.|:|:||.:||:.|||||.:||..||:|||:|..|:|: .|||:||
Zfish   201 ---------GPAKFHVLFLLFVALMFFVSLMFLFGYHCWLVAKNRSTLEAFSPPVFQ-NGPDRNG 255

  Fly   276 YNLGRYANFCEVFGDDWQYWFLPVFSSRGDGYSYP 310
            :|:|...|..:|||:..:.||:|||:|:|||:.:|
Zfish   256 FNVGLNKNLRQVFGEHKKLWFIPVFTSQGDGHYFP 290

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1407	NP_001286264.1	zf-DHHC	129..259	CDD:279823	72/129 (56%)
zdhhc15b	NP_001071249.1	zf-DHHC	16..292	CDD:303066	136/289 (47%)
zdhhc15b	NP_001071249.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	305..332
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170593733
Domainoid	1	1.000	174	1.000	Domainoid score	I3619
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	331	1.000	Inparanoid score	I2418
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1491968at2759
OrthoFinder	1	1.000	-	-		FOG0000300
OrthoInspector	1	1.000	-	-		otm24759
orthoMCL	1	0.900	-	-		OOG6_100499
Panther	1	1.100	-	-	O	PTHR22883
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1716
SonicParanoid	1	1.000	-	-		X260
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	14	13.790