DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG1407 and Zdhhc1

DIOPT Version :9

Sequence 1:NP_001286264.1 Gene:CG1407 / 36043 FlyBaseID:FBgn0033474 Length:452 Species:Drosophila melanogaster
Sequence 2:NP_001365935.1 Gene:Zdhhc1 / 70796 MGIID:1918046 Length:484 Species:Mus musculus


Alignment Length:501 Identity:98/501 - (19%)
Similarity:163/501 - (32%) Gaps:154/501 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly    31 VIAWSYYAYVVELCIRNSENRIGMIFMLLFYHLFLTLFMW-------------SYWRTIMTSVGR 82
            ::||..|.:...:       ..|::..||.:|       |             .:....:|:|..
Mouse    50 IVAWLLYLFFAVI-------GFGVLVPLLPHH-------WVPAGYACMGAIFAGHLVVHLTAVSI 100

  Fly    83 IPDQWRIPDEEVSRLFRADSPDTQKRILNNFARDLPVTNRTMNGSV---RFCEKCKIIKPDRAHH 144
            .|....:.|:                   :::..||:.||:.:..|   ..|..|.:....|:.|
Mouse   101 DPADANVRDK-------------------SYSGPLPIFNRSQHAHVIEDLHCNLCDVDVSARSKH 146

  Fly   145 CSVCSCCVLKMDHHCPWVNNCVNFYNYKYFVLFLGYALVYCLYVAFTSLHDFVEFWKVGAYDNNG 209
            ||.|:.||...||||.|:||||...||:.|:..:..||:..|.:...:.:.||||:         
Mouse   147 CSACNKCVCGFDHHCKWLNNCVGERNYRLFLHSVASALLGVLLLVLVATYVFVEFF--------- 202

  Fly   210 YSAQGQLNASGMGRFHIL-------FLF---------------FIAIMFAISLVS------LFGY 246
               ...:.......|.:|       |:|               ..|::..:.|:|      |..:
Mouse   203 ---VNPMRLRTNQHFEVLKNHTDVWFVFLPAAPVETQAPAILALAALLILLGLLSTALLGHLLCF 264

  Fly   247 HIYLVLVNRTTLE---SFRAPIFRVGGPDKNGYNLGRYANFC--EVFGDDWQYWFLPVFSSRGDG 306
            ||||:....||.|   ..|        |.:......:....|  :|.......:::..||     
Mouse   265 HIYLMWHKLTTYEYIVQHR--------PAQEAKETHKELESCPRKVRSIQEMEFYMRTFS----- 316

  Fly   307 YSYPTSSDQSRVS--TSSPTQRYDAMGDTTTSRLDGNPT-------------------------- 343
            :..|..|.|:|.:  .::|:|.....|.........:.|                          
Mouse   317 HVRPEPSGQARTAALNANPSQFLATQGQVEPPLPSSSDTLALPPRIQPQKKRKRRVYRLPRSGVL 381

  Fly   344 DKLIGASPLDTTNHHHNQSPHQVRSTSVLPTQL-----LQIQPPSTCRDELNERQQKLANGQSLD 403
            |:.:....|..|.....:|.....|||..|...     ......:...:|:...|.:|.:     
Mouse   382 DRELPLPRLRETGTPSRRSSSSSDSTSASPVHAGGSAGAYYSASAESMEEIPVAQTRLGS----- 441

  Fly   404 CSTPAAMSSPDERG-VNGAAVYIEMIGDHPLTSADPAKGFPRPPNG 448
                ||:.:|..|| .:|.|:...    .|.....|:.|.|..|.|
Mouse   442 ----AALGAPGARGRESGLALQAR----SPAVFVSPSSGEPGTPGG 479

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG1407NP_001286264.1 zf-DHHC 129..259 CDD:279823 42/157 (27%)
Zdhhc1NP_001365935.1 Mediates interaction with STING1. /evidence=ECO:0000250|UniProtKB:Q8WTX9 1..268 55/262 (21%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..38
DHHC 126..281 CDD:396215 44/166 (27%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 341..415 10/73 (14%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 444..484 11/40 (28%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C167848299
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
32.840

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