DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1407 and Zdhhc6

DIOPT Version :9

Sequence 1:	NP_001286264.1	Gene:	CG1407 / 36043	FlyBaseID:	FBgn0033474	Length:	452	Species:	Drosophila melanogaster
Sequence 2:	NP_001028745.1	Gene:	Zdhhc6 / 66980	MGIID:	1914230	Length:	413	Species:	Mus musculus

Alignment Length:	353	Identity:	84/353 - (23%)
Similarity:	142/353 - (40%)	Gaps:	110/353 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 WIPVLFITAVIAWSYYAYVVELCIRNSENRIGMIFMLLFY---HL------FLTLFMW------S 71
            |.|::.:.          |:.:|     :.:.||..:|:|   |.      |:.|..|      :
Mouse    22 WGPIIALG----------VIAIC-----STMAMIDSVLWYWPLHTTGGSVNFIMLINWTVMILYN 71

  Fly    72 YWRTIMTSVGRIPDQWRIPDEEVSRLFRADSPDTQKRILNNFARDLPVTNRTMNGSVRFCEKCKI 136
            |:..:....|.:|..|: |::....::                             :::|:.|:.
Mouse    72 YFNAMFAGPGFVPRGWK-PEKSQDSMY-----------------------------LQYCKVCQA 106

  Fly   137 IKPDRAHHCSVCSCCVLKMDHHCPWVNNCVNFYNYKYFVLFLGYALVYCLYVAF-------TSLH 194
            .|..|:|||..|:.||:||||||||:|||....|:..|.|||..|.:.|.:.||       |.|:
Mouse   107 YKAPRSHHCRKCNRCVMKMDHHCPWINNCCGHQNHASFTLFLLLAPLGCTHAAFIFVMTMYTQLY 171

  Fly   195 DFVEF-WKVGAYDNNGYSAQGQLNAS----------GMGRF-HILFLFFIAIMFAISLVSLFGYH 247
            :.:.| |.....|         ::|:          |:..| ..||...:|:...|::..||...
Mouse   172 NRLSFGWNTVKID---------MSAARRDPPPIVPFGLAAFAATLFALGLALGTTIAVGMLFFIQ 227

  Fly   248 IYLVLVNRTTLESFRAPIFRVGGPDKNGYNLGRYANFCEVF------GDDWQYWFLPVFS----S 302
            |.::|.|:|::||:         .::...:..:|....|||      |..|:. |..||:    .
Mouse   228 IKIILRNKTSIESW---------IEEKAKDRIQYYQLDEVFIFPYDMGSKWKN-FKQVFTWSGVP 282

  Fly   303 RGDGYSYP--TSSDQSRVSTSSPTQRYD 328
            .|||..:|  ...||..::.....|:.|
Mouse   283 EGDGLEWPIREGCDQYSLTIEQLKQKAD 310

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1407	NP_001286264.1	zf-DHHC	129..259	CDD:279823	48/148 (32%)
Zdhhc6	NP_001028745.1	DHHC	95..241	CDD:366691	49/183 (27%)
		SH3_2	317..396	CDD:369452
		Di-lysine motif. /evidence=ECO:0000250\|UniProtKB:Q9H6R6	410..413
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1491968at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820