DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1407 and Hip14

DIOPT Version :9

Sequence 1:	NP_001286264.1	Gene:	CG1407 / 36043	FlyBaseID:	FBgn0033474	Length:	452	Species:	Drosophila melanogaster
Sequence 2:	NP_001261910.1	Gene:	Hip14 / 39747	FlyBaseID:	FBgn0259824	Length:	655	Species:	Drosophila melanogaster

Alignment Length:	371	Identity:	81/371 - (21%)
Similarity:	122/371 - (32%)	Gaps:	122/371 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 DDHRRRKTPCGFCMAVFKWIPVLFITAVIAWSYY-----AYVVELCIRNSENRIGMIFMLLFYHL 63
            |:|.....|....:|...|.       .:.|..|     ::...:|.        :|..||.:..
  Fly   343 DEHLMALLPLSVYLATKAWF-------YVTWLMYIDDAVSFTATVCF--------LISSLLLWVC 392

  Fly    64 FLTLFMWSYWRTIMTSVGRIPDQWRIPDEEVSRLFRADSPDTQKRILNNFARDLPVTNRTMNG-- 126
            ||                   ..|: .|..:.|      |..::|    |...:.::.|...|
  Fly   393 FL-------------------KSWK-GDPGIIR------PTREQR----FKTIIELSERGGIGFE 427

  Fly   127 SVRFCEKCKIIKPDRAHHCSVCSCCVLKMDHHCPWVNNCVNFYNYKYFVLFLGYALVYCLYVAFT 191
            ...||..|.:.:|.|:.|||||..||.:.|||||||.||:...|:.||:.||...|:.|.::.:.
  Fly   428 PASFCSGCLVRRPIRSKHCSVCDRCVARFDHHCPWVGNCIGLKNHSYFMGFLWMLLIMCAWMLYG 492

  Fly   192 SLHDFVEFWKVGAYDNNG-YSAQGQLNA-----SGMGRFHILFLFFIAIMFAISLVSLFGYHIYL 250
            ....:|....|...|..| ..|.|..:|     .|....|:.::..:.|.....::.|
  Fly   493 GSKYYVNQCNVRFDDFLGAMRAIGNCDAWVGWVMGNALLHMSWVILLTICQTYQVICL------- 550

  Fly   251 VLVNRTTLESFRAPIFRVGGPDKNGYNLGRYANF----------------------CEVFG---- 289
               ..||.|..               |.|||.:|                      |..||
  Fly   551 ---GMTTNERM---------------NRGRYRHFQAKGGHSPFTRGPIQNLVDFLECSCFGLVQP 597

  Fly   290 --DDWQYWFLPVFSSRGDGYSYPTSSDQSRVSTSSPTQRYDAM-GD 332
              .||..::      ..|..::.|...:..:|...|    |.| ||
  Fly   598 KRVDWMNYY------DYDAQTHQTIEKEPLLSVDCP----DGMAGD 633

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1407	NP_001286264.1	zf-DHHC	129..259	CDD:279823	41/135 (30%)
Hip14	NP_001261910.1	ANK	52..165	CDD:238125
		Ank_2	52..142	CDD:289560
		ANK repeat	77..108	CDD:293786
		ANK repeat	110..142	CDD:293786
		ANK	114..233	CDD:238125
		Ank_2	116..209	CDD:289560
		ANK repeat	144..175	CDD:293786
		ANK repeat	177..209	CDD:293786
		Ank_5	198..251	CDD:290568
		ANK repeat	212..244	CDD:293786
		zf-DHHC	426..559	CDD:279823	42/157 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810