DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1407 and Zdhhc18

DIOPT Version :9

Sequence 1:	NP_001286264.1	Gene:	CG1407 / 36043	FlyBaseID:	FBgn0033474	Length:	452	Species:	Drosophila melanogaster
Sequence 2:	XP_038966311.1	Gene:	Zdhhc18 / 362613	RGDID:	1309334	Length:	482	Species:	Rattus norvegicus

Alignment Length:	461	Identity:	103/461 - (22%)
Similarity:	155/461 - (33%)	Gaps:	152/461 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 RRKTPCGFCM------AVFKWIPVLFITAVIAWSYYAYVVELCIRNSENRIGMIFMLLFYHLFLT 66
            |.:..||..:      .||....:|.::..|.  ::.:......|.....|.:|..:||:.:...
  Rat    74 RNRFYCGGRLMLAGHGGVFALTLLLILSTTIL--FFIFDCPYLARTLTLAIPIIAAILFFFVMSC 136

  Fly    67 LFMWSYWRTIMTSVGRIPDQWRIPDEEVSRLFRADSPDTQKRILNNFA---RDLPVTNRTM-NG- 126
            |...|:     |..|.:|           |....::...:|:|.|..:   |..|.|...| ||
  Rat   137 LLQTSF-----TDPGILP-----------RATICEAAALEKQIDNTGSSTYRPPPRTREVMINGQ 185

  Fly   127 --SVRFCEKCKIIKPDRAHHCSVCSCCVLKMDHHCPWVNNCVNFYNYKY---FVLFLGYALVY-- 184
              .:::|..||:.:|.|..|||||..||.:.|||||||.|||...||::   |:|.|.:...:
  Rat   186 MVKLKYCFTCKMFRPPRTSHCSVCDNCVERFDHHCPWVGNCVGRRNYRFFYAFILSLSFLTAFIF 250

  Fly   185 -CLYVAFTSLHDFVEFWKVGAYDNNGYSAQGQLNASGMGRFHILFLFFIAIMFAI-SLVSLFGYH 247
             |:....|.|                  :||....|.:.:.....|..:...|:| |::.|.|:|
  Rat   251 ACVVTHLTLL------------------SQGSNFLSALKKTPASVLELVICFFSIWSILGLSGFH 297

  Fly   248 IYLVLVNRTTLESFRAPIFRVGGPDKNGYNLGRYANFCEVFGDDWQYWFLPVFSSRGDGYSYPTS 312
            .|||..|.||.|..:.                           .|.       |.||...|....
  Rat   298 TYLVASNLTTNEDIKG---------------------------SWS-------SKRGGEASVNPY 328

  Fly   313 SDQSRVSTSSPTQRYDAMGDTTTSRLDGNPTDKLIGASP---LDTTNHHHNQSPHQVRSTSVLPT 374
            |.:|.::                     |....|.|..|   :|....        |:|.:|||:
  Rat   329 SHKSIIT---------------------NCCAVLCGPLPPSLIDRRGF--------VQSDTVLPS 364

  Fly   375 QLLQIQPPSTCRDELNERQQKLANGQSLDCSTPAAMSSPDERGVNGAAVYIEMIGDHPLTSADPA 439
            .:...:|....:                    |.|..:|..|||...         ||....: |
  Rat   365 PIRSDEPACGAK--------------------PDASMAPGLRGVRRT---------HPSLDLE-A 399

  Fly   440 KGFPRP 445
            ...|.|
  Rat   400 SSLPSP 405

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1407	NP_001286264.1	zf-DHHC	129..259	CDD:279823	46/136 (34%)
Zdhhc18	XP_038966311.1	DHHC	189..312	CDD:396215	47/140 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351911
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.840