DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1407 and Patsas

DIOPT Version :9

Sequence 1:	NP_001286264.1	Gene:	CG1407 / 36043	FlyBaseID:	FBgn0033474	Length:	452	Species:	Drosophila melanogaster
Sequence 2:	NP_001356957.1	Gene:	Patsas / 34634	FlyBaseID:	FBgn0029137	Length:	613	Species:	Drosophila melanogaster

Alignment Length:	331	Identity:	77/331 - (23%)
Similarity:	116/331 - (35%)	Gaps:	131/331 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 KWIP--------------------VLFITAVIAWSYYAYVVEL------CIRNSENRIGMIFMLL 59
            :|||                    .||:.:|:.|.|..|::..      .:|.|
  Fly   345 RWIPSVSESWGWLFGGAGDSKGPLFLFLFSVLLWGYPMYMIRAIPITWNILRRS----------- 398

  Fly    60 FYHLFLTLFMWSYWRTIMTSVGRIPDQWRIPDEEVSRLFRAD------SPDTQKRILNNFARDLP 118
             ::.|:      ||..:|..      .|.|.:       |.|      |.|...|.:    :.:|
  Fly   399 -HYCFI------YWNAVMWI------SWAIAN-------RRDPGYIPLSSDAYYRAI----KQIP 439

  Fly   119 VTNRTMNGSV---RFCEKCKIIKPDRAHHCSVCSCCVLKMDHHCPWVNNCVNFYNYKYFVLFL-- 178
            ..::....:|   |.|..|:.::|.||.||.||:.||...|||||::.|||...|..:|.||:
  Fly   440 YFDKLKKRNVMLTRLCHSCRCLRPLRAKHCRVCNRCVSYFDHHCPFIYNCVGLRNRMWFFLFVLS 504

  Fly   179 --------GYALVYCLYV-AFTSLHDFVEFWKVGAYDNNGYSAQGQLNASGMGRFHILFLFFIAI 234
                    .|...||:.: .||.|:                 ..|.:.|          :.|..:
  Fly   505 VAVNCSFTIYFACYCVMIEGFTMLY-----------------VLGLIEA----------VVFCGL 542

  Fly   235 MFAISLVSLFGYHIYLVLVNRTTLESF---RAPIFRVGGPDKNG-----YNLGRYANFCEVF--- 288
            .:.::..|:.  |   ..:|.||.|.|   |.|..|    ||.|     ::.|...|..|.|
  Fly   543 GWILTCTSIL--H---ACMNLTTNEMFNYKRYPYLR----DKRGRYQNPFSRGPILNLLEFFVCL 598

  Fly   289 ---GDD 291
               |||
  Fly   599 PDRGDD 604

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1407	NP_001286264.1	zf-DHHC	129..259	CDD:279823	38/140 (27%)
Patsas	NP_001356957.1	ANKYR	113..306	CDD:223738
		ANK repeat	148..181	CDD:293786
		ANK repeat	187..214	CDD:293786
		ANK repeat	216..247	CDD:293786
		ANK repeat	249..280	CDD:293786
		ANK repeat	282..314	CDD:293786
		Ank_4	283..336	CDD:316185
		DHHC	455..567	CDD:334580	39/143 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45467500
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR22883
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840