DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1407 and Zdhhc4

DIOPT Version :9

Sequence 1:	NP_001286264.1	Gene:	CG1407 / 36043	FlyBaseID:	FBgn0033474	Length:	452	Species:	Drosophila melanogaster
Sequence 2:	NP_001013141.1	Gene:	Zdhhc4 / 304291	RGDID:	1308389	Length:	343	Species:	Rattus norvegicus

Alignment Length:	334	Identity:	88/334 - (26%)
Similarity:	126/334 - (37%)	Gaps:	99/334 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 RKTPCGFCMAVFKWIPVLFIT---AVIA---------WSYYAYVVELCIRNSENRIGMI---FML 58
            |.||..|..||...:..||.|   |.:|         ::.|.|.|....|..|..:..:   ::|
  Rat    43 RVTPQCFQRAVQTLLHQLFHTRHPAFLALHLLLQGLVYAEYTYEVFSYCRELEFSLPCLLLPYVL 107

  Fly    59 LFYHL-FLTLFMWSYWRTIMTSVGRIPDQWRIPDEEVSRLFRADSPDTQKRI---LNNFARD--- 116
            |..:| |.||       |..|:.|.|                     |:..:   |..:..|
  Rat   108 LSVNLVFFTL-------TCSTNPGTI---------------------TKTNVLLLLQVYEFDEVM 144

  Fly   117 LPVTNRTMNGSVRFCEKCKIIKPDRAHHCSVCSCCVLKMDHHCPWVNNCVNFYNYKYFVLFL--- 178
            .|..:|        |..|.:.||.|:.||.||..||.:.||||.|||||:..:|..||:::|
  Rat   145 FPKNSR--------CSTCDLRKPARSKHCRVCDRCVHRFDHHCVWVNNCIGAWNTGYFLIYLLTL 201

  Fly   179 --GYALVYCLYVAF-------------TSLHDFVEFWKVGAYDNNGYSAQGQLNASGMGRFHILF 228
              ..|.:..|..||             |.|.|...|..|    :.|:..|....|..    .|:|
  Rat   202 TASAATIAILSAAFLLRLVAVSNLYQETYLDDLGRFQAV----DTGFLIQHLFLAFP----RIIF 258

  Fly   229 LFFIAIMFAISLVSLFGYHIYLVLVNRTTLESFRA--------PIFRVGGPD------KNGYNLG 279
            |....|:.::.|.....:.:||...|:||.|.:|.        |:. ...|.      :|.|:.|
  Rat   259 LLGFVIVLSLLLAGYLCFALYLAATNQTTNEWYRGDWAWCQHWPLV-AWSPSAEPQIHQNIYSHG 322

  Fly   280 RYANFCEVF 288
            .::|..|||
  Rat   323 LWSNLQEVF 331

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1407	NP_001286264.1	zf-DHHC	129..259	CDD:279823	46/147 (31%)
Zdhhc4	NP_001013141.1	zf-DHHC	151..292	CDD:279823	47/148 (32%)
Zdhhc4	NP_001013141.1	Di-lysine motif. /evidence=ECO:0000250\|UniProtKB:Q9NPG8	340..343
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351923
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.840