Protein Alignment CG1407 and ZDHHC1

DIOPT Version :10

• Sequence 1: NP_001286264.1
• Gene: CG1407 / 36043
• FlyBaseID: FBgn0033474
• Length: 452
• Species: Drosophila melanogaster
• Sequence 2: NP_037436.1
• Gene: ZDHHC1 / 29800
• HGNCID: 17916
• Length: 485
• Species: Homo sapiens
• Alignment Length: 273
• Identity: 61/273 - (22%)
• Similarity: 99/273 - (36%)
• Gaps: 89/273 - (32%)

  Fly    31 VIAWSYYAYVVELCIRNSENRIGMIFMLLFYHLFLTLFMW-------------SYWRTIMTSVGR 82
            ::||..|.:...:       ..|::..||.:|       |             .:....:|:|..
Human    53 IVAWLLYLFFAVI-------GFGILVPLLPHH-------WVPAGYACMGAIFAGHLVVHLTAVSI 103

  Fly    83 IPDQWRIPDEEVSRLFRADSPDTQKRILNNFARDLPVTNRTMNGSV---RFCEKCKIIKPDRAHH 144
            .|....:.|:                   ::|..||:.||:.:..|   ..|..|.:....|:.|
Human   104 DPADANVRDK-------------------SYAGPLPIFNRSQHAHVIEDLHCNLCNVDVSARSKH 149

  Fly   145 CSVCSCCVLKMDHHCPWVNNCVNFYNYKYFVLFLGYALVYCLYVAFTSLHDFVEFWKVGAYDNNG 209
            ||.|:.||...||||.|:||||...||:.|:..:..||:..|.:...:.:.||||:
Human   150 CSACNKCVCGFDHHCKWLNNCVGERNYRLFLHSVASALLGVLLLVLVATYVFVEFF--------- 205

  Fly   210 YSAQGQLNASGMGRFHIL-------FLF---------------FIAIMFAISLVS------LFGY 246
               ...:.......|.:|       |:|               ..|::..:.|:|      |..:
Human   206 ---VNPMRLRTNRHFEVLKNHTDVWFVFLPAAPVETQAPAILALAALLILLGLLSTALLGHLLCF 267

  Fly   247 HIYLVLVNRTTLE 259
            ||||:....||.|
Human   268 HIYLMWHKLTTYE 280

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1407	NP_001286264.1	DHHC	129..259	CDD:396215	42/157 (27%)
ZDHHC1	NP_037436.1	Mediates interaction with STING1. /evidence=ECO:0000269|PubMed:25299331	1..271		56/262 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..41
		DHHC	129..284	CDD:396215	44/164 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	324..358
		DPBB_RlpA_EXP_N-like	<362..>400	CDD:455124
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	462..485