DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1407 and Zdhhc13

DIOPT Version :9

Sequence 1:	NP_001286264.1	Gene:	CG1407 / 36043	FlyBaseID:	FBgn0033474	Length:	452	Species:	Drosophila melanogaster
Sequence 2:	NP_082307.1	Gene:	Zdhhc13 / 243983	MGIID:	1919227	Length:	622	Species:	Mus musculus

Alignment Length:	319	Identity:	75/319 - (23%)
Similarity:	123/319 - (38%)	Gaps:	93/319 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 WIPVLFITAVIAWSYYAYVVELCIRNSENRIGMIFMLLF--------YHLF---LTLFMWSYWRT 75
            ::|.:|:.:.|.|.:..:                |:|.|        |..|   :..|::.:::|
Mouse   346 YLPTVFLLSSIFWIFMTW----------------FILFFPDTAGSPLYFAFIFSIMAFLYFFYKT 394

  Fly    76 IMTSVGRIPDQWRIPDEEVSRLFRADSPDTQKRILNNFARDLPVTNRTMNGSVRFCEKCKIIKPD 140
            ..|..|                |...|.:.:|..:...|....:..||      ||..|.|.||.
Mouse   395 WATDPG----------------FTKASEEERKVNIVTLAETGSLDFRT------FCTSCLIRKPL 437

  Fly   141 RAHHCSVCSCCVLKMDHHCPWVNNCVNFYNYKYFVLFLGYALVYCLYVAFTSLHDFVEFWK---V 202
            |:.||.||:.||.:.|.||.|...|:.|.|:.:::.||....:.|.::.:.|   || :|.   .
Mouse   438 RSLHCHVCNSCVARFDQHCFWTGRCIGFGNHHHYIFFLLSLSMVCDWIIYGS---FV-YWSNHCA 498

  Fly   203 GAYDNNG-YSAQGQLNASG--------MGRFHILFLFFIAI--MFAISLVSLFGY-HIYLVLVNR 255
            ..:..:| ::...|:.|..        :..||..:..|:.|  :|.|:.:.|..: .|.|:..:|
Mouse   499 TTFKEDGLWTYLNQIVACSPWVLYIFMLAAFHFSWSTFLLINQLFQIAFLGLTSHERISLLKQSR 563

  Fly   256 ---TTLESFRAPIFRVGGPDKNGYNLG---RYANF--CEVFG------DDWQYWFLPVF 300
               .||...:.|           ||||   ..|:|  |..||      .||...:..||
Mouse   564 HMKQTLSLRKTP-----------YNLGFTQNLADFFQCGCFGLVKPCIIDWTSQYTMVF 611

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1407	NP_001286264.1	zf-DHHC	129..259	CDD:279823	41/147 (28%)
Zdhhc13	NP_082307.1	ANK 1. /evidence=ECO:0000250\|UniProtKB:Q8IUH5	43..78
		ANK	79..192	CDD:238125
		ANK repeat	81..112	CDD:293786
		ANK 2. /evidence=ECO:0000255	81..110
		Ank_2	86..179	CDD:289560
		ANK repeat	114..146	CDD:293786
		ANK 3. /evidence=ECO:0000255	115..144
		ANK repeat	148..179	CDD:293786
		ANK 4. /evidence=ECO:0000255	148..177
		ANK	176..>269	CDD:238125
		ANK repeat	181..247	CDD:293786
		ANK 5. /evidence=ECO:0000255	181..211
		Ank_5	202..257	CDD:290568
		ANK 6. /evidence=ECO:0000255	216..245
		ANK 7. /evidence=ECO:0000255	249..277
		zf-DHHC	423..556	CDD:279823	39/142 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810