DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1407 and si:ch211-223a10.1

DIOPT Version :9

Sequence 1:	NP_001286264.1	Gene:	CG1407 / 36043	FlyBaseID:	FBgn0033474	Length:	452	Species:	Drosophila melanogaster
Sequence 2:	XP_009305694.1	Gene:	si:ch211-223a10.1 / 101884554	ZFINID:	ZDB-GENE-090313-86	Length:	544	Species:	Danio rerio

Alignment Length:	230	Identity:	54/230 - (23%)
Similarity:	98/230 - (42%)	Gaps:	46/230 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    62 HLFLTLF---MWSYWRTIMTSVGRIPDQWRIPDEEVSRLFRADSPDTQKRILNNFARDLPVTNRT 123
            ||.|..|   ...:|:.:..|.|::.|                 .||..|.  :...||....::
Zfish   338 HLSLVHFCVLAGLFWKVLKQSPGQLKD-----------------ADTDSRF--SSIGDLMEAGQS 383

  Fly   124 MNGSVRFCEKCKIIKPDRAHHCSVCSCCVLKMDHHCPWVNNCVNFYNYKYFVLFLGYALVYCLYV 188
            .:   |||..|::|:.:...||.:|..|:...||||.::|.||...|::.|:|||...::..|..
Zfish   384 PD---RFCIYCELIQVENCKHCRLCDMCIKDYDHHCLFINQCVGRENHRTFILFLMSMVMAHLIF 445

  Fly   189 AFTSLHDFVEFWKVGAYDNNGYSAQGQLNASGMGRFHILFLFFIAIMFAISLVSLF--GYHI--Y 249
            ..:::  |..:.||.....:.:.:.....|            ::.::..::|:|||  |:.:  .
Zfish   446 ILSAI--FYLYLKVSGLQLSDWGSVAGREA------------WVLLLTLLNLLSLFWVGWLLGEQ 496

  Fly   250 LVLVNRTTLESFRAPIFRVGGPDKNGYNLGRYANF 284
            |..::|.|...:|.  :.:.||.|. ..||...:|
Zfish   497 LDAISRGTTTYYRR--YDLKGPSKR-QRLGTVVSF 528

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1407	NP_001286264.1	zf-DHHC	129..259	CDD:279823	34/133 (26%)
si:ch211-223a10.1	XP_009305694.1	ANK repeat	7..36	CDD:293786
		Ank_2	9..102	CDD:289560
		ANK	39..159	CDD:238125
		ANK repeat	39..69	CDD:293786
		ANK repeat	71..102	CDD:293786
		Ank_2	76..162	CDD:289560
		ANK repeat	138..170	CDD:293786
		Ank_4	139..192	CDD:290365
		zf-DHHC	384..509	CDD:279823	34/141 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900