DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1407 and zdhhc17

DIOPT Version :9

Sequence 1:	NP_001286264.1	Gene:	CG1407 / 36043	FlyBaseID:	FBgn0033474	Length:	452	Species:	Drosophila melanogaster
Sequence 2:	NP_001121854.1	Gene:	zdhhc17 / 100148543	ZFINID:	ZDB-GENE-070424-194	Length:	620	Species:	Danio rerio

Alignment Length:	342	Identity:	74/342 - (21%)
Similarity:	130/342 - (38%)	Gaps:	97/342 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 MAVFKWIPVLFITAVIAWSYYAYVVELCIRNSENRIGMIFMLLFYHLFLTLFMWSYWRTIMTSVG 81
            |....|:.|.|::.    |::.:.:     :|...:| |::...:.:::|.|.| :|..:.....
Zfish   322 MYAVMWLVVQFLSK----SFFDHSM-----HSALPLG-IYLATKFWMYITWFYW-FWNDLPFVTI 375

  Fly    82 RIP-------------DQWRIPDEEVSRLFRADSPDTQKRILNNFARDLPVTNRTMNGSVRFCEK 133
            .:|             ..|: .|..:.:........|...:....:.||.:          ||..
Zfish   376 HLPFLLNSLALFYNFGKSWK-SDPGIIKASEEQKKKTIVELAETGSLDLSI----------FCST 429

  Fly   134 CKIIKPDRAHHCSVCSCCVLKMDHHCPWVNNCVNFYNYKYFVLFLGYALVYCLYVAFTSLHDFVE 198
            |.|.||.|:.||:||:.|:.|.|||||||.|||...|::|   |:|| |.:.|.:....::..:.
Zfish   430 CLIRKPIRSKHCAVCNRCIAKFDHHCPWVGNCVGSGNHRY---FMGY-LFFLLCMICWMMYGCIC 490

  Fly   199 FWKV---GAYDNNGYSAQGQLNASGMGRFHILFLFFIAI----MFAISLVSLFGYHIYLVLV--- 253
            :|::   .:|..:|:               .:::..||.    ||.:.|.|:|.:....||:
Zfish   491 YWRIHCATSYTKDGF---------------WIYITQIATCSPWMFWMFLNSVFHFMWVAVLIMCQ 540

  Fly   254 ---------------NRTTLESFRAPIFRVGGPDKNGYNLGRYANFCEVF-----------GDDW 292
                           |....:.|:.....:..|    :|.|...|..:.|           ..||
Zfish   541 LYQIAVLGITTNERMNARRYKHFKVTATSIESP----FNHGCMRNLIDFFELRCCGLLRPVPIDW 601

  Fly   293 --QYWFLPVFSSRGDGY 307
              || .:....:.|.||
Zfish   602 TSQY-TIEYDQTSGSGY 617

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1407	NP_001286264.1	zf-DHHC	129..259	CDD:279823	43/154 (28%)
zdhhc17	NP_001121854.1	PHA02874	<59..>253	CDD:165205
		ANK repeat	77..108	CDD:293786
		ANK 1. /evidence=ECO:0000255	77..106
		ANK repeat	110..142	CDD:293786
		ANK 2. /evidence=ECO:0000255	111..140
		ANK repeat	144..175	CDD:293786
		ANK 3. /evidence=ECO:0000255	144..173
		Ank_2	150..243	CDD:403870
		ANK repeat	177..209	CDD:293786
		ANK 4. /evidence=ECO:0000255	177..207
		ANK repeat	212..243	CDD:293786
		ANK 5. /evidence=ECO:0000255	212..241
		ANK 6. /evidence=ECO:0000255	245..274
		DHHC	426..556	CDD:396215	42/148 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810