Protein Alignment CG12128 and SPOUT1

DIOPT Version :10

• Sequence 1: NP_610543.1
• Gene: CG12128 / 36042
• FlyBaseID: FBgn0033473
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: NP_057474.2
• Gene: SPOUT1 / 51490
• HGNCID: 26933
• Length: 376
• Species: Homo sapiens
• Alignment Length: 372
• Identity: 181/372 - (48%)
• Similarity: 256/372 - (68%)
• Gaps: 23/372 - (6%)

  Fly    15 RPIGPHK-----SWKKVNEERKALKRQRKQDKLLKELQQAKEAESQAGKAANE---VQAKDKPNP 71
            ||.||.:     .|:|..:::|..|::.|..||:|:|::.:..|.||.:...|   .:.:|:..|
Human     8 RPCGPGEHGQRIEWRKWKQQKKEEKKKWKDLKLMKKLERQRAQEEQAKRLEEEEAAAEKEDRGRP 72

  Fly    72 STLSIAVPGSILENAQSNELRAYVAGQIARAACIFRVNEVIVFDDVGIATARETKRSYEADGEGS 136
            .|||:|:|||||:||||.|||.|:|||||||..||.|:|::|||:.|    ::.|   ..:||.:
Human    73 YTLSVALPGSILDNAQSPELRTYLAGQIARACAIFCVDEIVVFDEEG----QDAK---TVEGEFT 130

  Fly   137 STGTVRSSSLQLARILQYLECPQYLRKYFFPLHKDLKYSGLLNPLDTPHHLRQQSKFRYREGVIC 201
            ..|....:.:|||||||||||||||||.|||.|:||:::|||||||:|||:||..:..:|||::.
Human   131 GVGKKGQACVQLARILQYLECPQYLRKAFFPKHQDLQFAGLLNPLDSPHHMRQDEESEFREGIVV 195

  Fly   202 DKKAKEGH-SYANVGLLNDVLVDKAIEPGVRVTVKM-EPQSESCRKQRGTLVSPDEPRRETGVYW 264
            |:..:.|| |:.|.|:..:|.:||.:|||:||||:: :.|...|:...|.:||..:||.:.|:||
Human   196 DRPTRPGHGSFVNCGMKKEVKIDKNLEPGLRVTVRLNQQQHPDCKTYHGKVVSSQDPRTKAGLYW 260

  Fly   265 GYQVRIAHSMSEIFTKSPYATGYDVTVGTSDRGTNV--HEVPNRSYNFNHMLIVFGGLQGLESAL 327
            ||.||:|..:|.:|.::|:..|||:|:|||:||::|  .::|    ||.|.|:|||||||||:..
Human   261 GYTVRLASCLSAVFAEAPFQDGYDLTIGTSERGSDVASAQLP----NFRHALVVFGGLQGLEAGA 321

  Fly   328 ANDEKLTVDDPELLFDHYVNVLPRQGSRTIRTEEALLIALAALQEKL 374
            ..|..|.|.:|.:|||.|||..|.|||||||||||:||:|||||..|
Human   322 DADPNLEVAEPSVLFDLYVNTCPGQGSRTIRTEEAILISLAALQPGL 368

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12128	NP_610543.1	Methyltrn_RNA_3	73..361	CDD:460611	151/291 (52%)
SPOUT1	NP_057474.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..33		7/24 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	49..71		5/21 (24%)
		Methyltrn_RNA_3	74..364	CDD:460611	158/300 (53%)