Protein Alignment Pka-R2 and PRKG2

DIOPT Version :9

• Sequence 1: NP_523671.1
• Gene: Pka-R2 / 36041
• FlyBaseID: FBgn0022382
• Length: 377
• Species: Drosophila melanogaster
• Sequence 2: XP_016863902.1
• Gene: PRKG2 / 5593
• HGNCID: 9416
• Length: 774
• Species: Homo sapiens
• Alignment Length: 367
• Identity: 99/367 - (26%)
• Similarity: 184/367 - (50%)
• Gaps: 26/367 - (7%)

  Fly    13 EELKEVLLQFSISFLVEQPPDVIDYAVEYFTKLQSERPSVSHTD-----QSTDDQ--LSVNSQDA 70
            :||:|.|.:.::: :.|...::.:..:: ..|||    .|.|..     |::.|:  |.|:.:.:
Human    52 KELREQLSKQTVA-IAELTEELQNKCIQ-LNKLQ----DVVHMQGGSPLQASPDKVPLEVHRKTS 110

  Fly    71 DAEPPVMASSRR---KSVFAE----AYDPEADDDDDGATAVFPKTDEQRARLVESVKNVLLFRSL 128
            ..   |...|||   ..|.||    .||.....:.....|...|...::..:.:::......:.|
Human   111 GL---VSLHSRRGAKAGVSAEPTTRTYDLNKPPEFSFEKARVRKDSSEKKLITDALNKNQFLKRL 172

  Fly   129 EKEQMNQVLDAMFERKVQPGDFIIRQGDDGDNFYVIESGVYKVYINDKHINTYNHTGLFGELALL 193
            :.:|:..:::.|:.|..|.|.:||:||:.|::.:|:..|..:|:..:|.:::......|||||:|
Human   173 DPQQIKDMVECMYGRNYQQGSYIIKQGEPGNHIFVLAEGRLEVFQGEKLLSSIPMWTTFGELAIL 237

  Fly   194 YNMPRAATVQAETSGLLWAMDRQTFRRILLKSAFRKRKMYEELLNSVPMLKALQNYERMNLADAL 258
            ||..|.|:|:|.|:...||:||:.|:.|:.::|..:.:.|...|.||.:||.|...:...:.|.|
Human   238 YNCTRTASVKAITNVKTWALDREVFQNIMRRTAQARDEQYRNFLRSVSLLKNLPEDKLTKIIDCL 302

  Fly   259 VSKSYDNGERIIKQGDAADGMYFIEEGTVSVRMDQD--DAEVEISQLGKGQYFGELALVTHRPRA 321
            ..:.||.|:.||::|:.....:.:.:|.|.|....:  |....|..|.||:||||.||::...|:
Human   303 EVEYYDKGDYIIREGEEGSTFFILAKGKVKVTQSTEGHDQPQLIKTLQKGEYFGEKALISDDVRS 367

  Fly   322 ASVYATGGVVKLAFLDVKAFERLLGPCMDIMKRNIDDYESQL 363
            |::.|....|....:|.:.|.:.:|...::.| .::.|.:.|
Human   368 ANIIAEENDVACLVIDRETFNQTVGTFEELQK-YLEGYVANL 408

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pka-R2	NP_523671.1	DD_RII_PKA	11..49	CDD:213046	8/35 (23%)
		CAP_ED	124..233	CDD:237999	35/108 (32%)
		CAP_ED	242..356	CDD:237999	33/115 (29%)
PRKG2	XP_016863902.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0664
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810