Protein Alignment Pka-R2 and prkar1ab

DIOPT Version :10

• Sequence 1: NP_523671.1
• Gene: Pka-R2 / 36041
• FlyBaseID: FBgn0022382
• Length: 377
• Species: Drosophila melanogaster
• Sequence 2: NP_001017732.1
• Gene: prkar1ab / 550427
• ZFINID: ZDB-GENE-050417-238
• Length: 379
• Species: Danio rerio
• Alignment Length: 383
• Identity: 142/383 - (37%)
• Similarity: 219/383 - (57%)
• Gaps: 37/383 - (9%)

  Fly     1 MSSDSSRRIQ----------VPEELKEVLLQFSISFLVEQPPDVIDYAVEYFTKLQSE------- 48
            :||:..:.::          |.:.||:.::|...|    :|...:.:..|||.:|:.|
Zfish     6 VSSEEEKSLRECEVYVQKHNVQQLLKDCIVQLCTS----RPDRPMAFLREYFERLEKEESKQLLN 66

  Fly    49 RPSVSHTDQSTDDQLSVNSQDADAEPPVMASSRRKSVFAEAYDPEADDDDDGAT---AVFPKTDE 110
            :...|....|.:|::|     ....|.|....||.::.||.|     .::|.|:   .|.||..:
Zfish    67 QQKASSRSDSREDEVS-----PPMNPVVKGRRRRGAISAEVY-----TEEDAASYVRKVIPKDYK 121

  Fly   111 QRARLVESVKNVLLFRSLEKEQMNQVLDAMFERKVQPGDFIIRQGDDGDNFYVIESGVYKVYIND 175
            ..|.|.::::..:||..|:..:.:.:.||||......|:.:|:|||:|||||||:.|...||:|.
Zfish   122 TMAALAKAIEKNVLFSHLDDNERSDIFDAMFPVTYIAGEIVIQQGDEGDNFYVIDQGEMDVYVNS 186

  Fly   176 KHINTYNHTGLFGELALLYNMPRAATVQAETSGLLWAMDRQTFRRILLKSAFRKRKMYEELLNSV 240
            :...:....|.||||||:|..||||||:|:|:..||.:||.::||||:.|..||||||||.|:.|
Zfish   187 EWATSIGEGGSFGELALIYGTPRAATVRAKTNVKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKV 251

  Fly   241 PMLKALQNYERMNLADALVSKSYDNGERIIKQGDAADGMYFIEEGTVSV--RMDQDDAEVEISQL 303
            .:|::|..:||:.:||||....:::.::|:.||:..|..:.|.||..:|  |..:::..||:.:|
Zfish   252 SILESLDKWERLTVADALEPVQFEDSQKIVVQGEPGDEFFIILEGCAAVLQRRSENEEFVEVGRL 316

  Fly   304 GKGQYFGELALVTHRPRAASVYATGGVVKLAFLDVKAFERLLGPCMDIMKRNIDDYES 361
            |...||||:||:.:|||||:|.|. |.:|...||...|||:||||.||:||||..|.|
Zfish   317 GPSDYFGEIALLMNRPRAATVVAR-GPLKCVKLDRPRFERVLGPCSDILKRNIQQYNS 373

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pka-R2	NP_523671.1	DD_RII_PKA	11..46	CDD:438520	9/34 (26%)
		CAP_ED	124..233	CDD:237999	52/108 (48%)
		CAP_ED	242..356	CDD:237999	49/115 (43%)
prkar1ab	NP_001017732.1	DD_RIalpha_PKA	13..62	CDD:438522	11/52 (21%)
		CAP_ED	135..244	CDD:237999	52/108 (48%)
		CAP_ED	253..368	CDD:237999	49/115 (43%)