DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pka-R2 and CG14693

DIOPT Version :9

Sequence 1:	NP_523671.1	Gene:	Pka-R2 / 36041	FlyBaseID:	FBgn0022382	Length:	377	Species:	Drosophila melanogaster
Sequence 2:	NP_001262467.1	Gene:	CG14693 / 41299	FlyBaseID:	FBgn0037837	Length:	586	Species:	Drosophila melanogaster

Alignment Length:	277	Identity:	59/277 - (21%)
Similarity:	94/277 - (33%)	Gaps:	102/277 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly   112 RARLVESVKNVLLFRSLEKEQMNQVLDAMFERKVQPGDFIIRQGDDGDNFYVIESGVYKVYINDK 176
            |||||..|:.:                     .|..|..||||.|.....:.:.:|...:..|:|
  Fly   105 RARLVPVVRLM---------------------PVDAGRIIIRQSDAPITVFFVLTGEVHMIKNEK 148

  Fly   177 HINTYNHTG------------LFGELALLYNMPRAATVQAETSGLLWAMDRQTFRRILLKSAFRK 229
                 |..|            :.|::.||..:.|..|.:|.|
  Fly   149 -----NQKGEGVVMGFLGAGDMMGDVELLEGIKRTHTFRAAT----------------------- 185

  Fly   230 RKMYEELLNSVPMLKALQNYERMNLADALVSKSYDNGERIIKQGDAADGMYFIEEGTVSVRMDQD 294
               |.|||       .|.:|:...:..|.::|.::..:|.:|   |.|...|::          |
  Fly   186 ---YCELL-------VLFDYDFAPILGAYMTKIWEEKKRALK---ALDYFDFLD----------D 227

  Fly   295 DAEVEISQLGKGQYFGELALVTHRPRAASVYATGGVVKLAFLDVKAFERLLGPCMDI---MKRNI 356
            |..||..:.|:.:.|..|..:....       .|.:..:.|  |.:.|.|:..|::|   |||..
  Fly   228 DQIVEACRYGRLKQFDPLDTIFCED-------IGSMTNVHF--VLSGECLILQCLNIKVTMKRGK 283

  Fly   357 DDY------ESQLVKIF 367
            ..|      |..:.|:|
  Fly   284 KVYDLLPASEGDVSKMF 300

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pka-R2	NP_523671.1	DD_RII_PKA	11..49	CDD:213046
		CAP_ED	124..233	CDD:237999	19/120 (16%)
		CAP_ED	242..356	CDD:237999	26/116 (22%)
CG14693	NP_001262467.1	Crp	90..>204	CDD:223736	31/157 (20%)
CG14693	NP_001262467.1	CAP_ED	97..204	CDD:237999	31/157 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0664
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900