DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Pka-R2 and CG4839

DIOPT Version :9

Sequence 1:	NP_523671.1	Gene:	Pka-R2 / 36041	FlyBaseID:	FBgn0022382	Length:	377	Species:	Drosophila melanogaster
Sequence 2:	NP_609349.1	Gene:	CG4839 / 34348	FlyBaseID:	FBgn0032187	Length:	1003	Species:	Drosophila melanogaster

Alignment Length:	368	Identity:	96/368 - (26%)
Similarity:	163/368 - (44%)	Gaps:	21/368 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 SDSSRRIQVPEELKEVLLQFSISFLVEQPPDVIDYAVEYFTKLQSERPSVSHTDQSTDDQLSVNS 67
            :||.||.:|     ..:...:|......||:::........:.:..........|....|.....
  Fly   301 TDSQRRRRV-----STMPDINIPPAPPLPPELLVPGTPLHLRKKRSMERQQQQKQQEQQQQQEIQ 360

  Fly    68 QDADAEPPVMASSRRKSVFAEAYDPEADDDDDGATAVFPKTDEQRARLVESV------------- 119
            |||......||.:......:::..|:....:.|...|.|....|....:||:
  Fly   361 QDATNSQDQMAGAEESHKSSDSSTPKTHRVEGGLIYVRPNFPIQSDIEIESIAKDEGTRNLIRTA 425

  Fly   120 --KNVLLFRSLEKEQMNQVLDAMFERKVQPGDFIIRQGDDGDNFYVIESGVYKVYINDKHINTYN 182
              :|..|...::||:...|::||.....:....|||:.::|...||...|.|.|....:.:.::.
  Fly   426 IERNDFLNNLMDKERKEMVINAMAPASYRKHSLIIREHEEGSEIYVSAEGQYDVIRGGQLVASFG 490

  Fly   183 HTGLFGELALLYNMPRAATVQAETSGLLWAMDRQTFRRILLKSAFRKRKMYEELLNSVPMLKALQ 247
            ...:|||||:|||.||.|:::|.|...:|.:.|:|||.|:..|..|:|:...:.|.|.|.|:...
  Fly   491 PATVFGELAILYNAPRQASIEAATDARVWKIARETFRAIMQISGSREREENLQFLRSAPFLQEFD 555

  Fly   248 NYERMNLADALVSKSYDNGERIIKQGDAADGMYFIEEGTVSV-RMDQDDAEVEISQLGKGQYFGE 311
            ....:.:.|.|..|.|:....|:::|:..:..|.|..|||:: ::|:...|..::...:|.||||
  Fly   556 QSLLLKVVDLLQRKFYETDSCIVREGELGNEFYIIRCGTVTIKKLDEQQQEQIVANRKRGDYFGE 620

  Fly   312 LALVTHRPRAASVYATGGVVKLAFLDVKAFERLLGPCMDIMKR 354
            .||:....|.|||||.....::..||.:||...||....:.::
  Fly   621 QALLNADVRQASVYADAPGTEVLMLDREAFISYLGTIKQLREK 663

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pka-R2	NP_523671.1	DD_RII_PKA	11..49	CDD:213046	4/37 (11%)
		CAP_ED	124..233	CDD:237999	37/108 (34%)
		CAP_ED	242..356	CDD:237999	33/114 (29%)
CG4839	NP_609349.1	Crp	428..577	CDD:223736	46/148 (31%)
		CAP_ED	431..539	CDD:237999	36/107 (34%)
		Crp	544..>650	CDD:223736	32/105 (30%)
		CAP_ED	550..663	CDD:237999	33/112 (29%)
		S_TKc	695..951	CDD:214567
		STKc_cGK	700..957	CDD:270724
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	43	1.000	Domainoid score	I744
eggNOG	1	0.900	-	-		E1_COG0664
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000531
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.810