Protein Alignment Pka-R2 and Pka-R1

DIOPT Version :10

• Sequence 1: NP_523671.1
• Gene: Pka-R2 / 36041
• FlyBaseID: FBgn0022382
• Length: 377
• Species: Drosophila melanogaster
• Sequence 2: XP_001688871.1
• Gene: Pka-R1 / 1277058
• VectorBaseID: AGAMI1_010888
• Length: 373
• Species: Anopheles gambiae
• Alignment Length: 355
• Identity: 146/355 - (41%)
• Similarity: 218/355 - (61%)
• Gaps: 22/355 - (6%)

  Fly    15 LKEVLLQFSISFLVEQPPDVIDYAVEYFTKLQSERPSVSHTDQST--DDQLSVNSQDADAEPPVM 77
            ||:.::|..:|    :|.:.|.:..:||.||:.|:..:..:.|:.  ||...::.....|.|||
Mosquito    27 LKDCIVQLCVS----RPENPIVFLRQYFQKLEREQAKLDASKQAVTPDDLDDLSPMPQTAVPPV- 86

  Fly    78 ASSRRKSVFAEAYDPEADDDDDGATA----VFPKTDEQRARLVESVKNVLLFRSLEKEQMNQVLD 138
              .||..:.||   |..::|   ||:    |.||..:..|.|.:::...:||..|::.:.:.:.|
Mosquito    87 --RRRGGISAE---PVTEED---ATSYVKKVVPKDYKTMAALSKAIAKNVLFSHLDENERSDIFD 143

  Fly   139 AMFERKVQPGDFIIRQGDDGDNFYVIESGVYKVYINDKHINTYNHTGLFGELALLYNMPRAATVQ 203
            |||.....||:.||:|||:|||||||:.|..:|::|::.:.|.:..|.||||||:|..||||||:
Mosquito   144 AMFPCNFLPGEPIIQQGDEGDNFYVIDIGEVEVFVNNEQVTTISEGGSFGELALIYGTPRAATVR 208

  Fly   204 AETSGLLWAMDRQTFRRILLKSAFRKRKMYEELLNSVPMLKALQNYERMNLADALVSKSYDNGER 268
            |:|...||.:||.::||||:.|..||||||||.|:.|.:|::|..:||:.:||||...|:::||.
Mosquito   209 AKTDVKLWGIDRDSYRRILMGSTIRKRKMYEEFLSRVSILESLDKWERLTVADALEPVSFEDGET 273

  Fly   269 IIKQGDAADGMYFIEEGTVSVRMDQDDAE--VEISQLGKGQYFGELALVTHRPRAASVYATGGVV 331
            |::||:..:..|.|.||..:|...:.|:|  .|:.:||...||||:||:..|||||:|.|. |.:
Mosquito   274 IVRQGEPGNDFYIIVEGCATVMQKRGDSEEAAEVGRLGPSDYFGEIALLLDRPRAATVIAR-GPL 337

  Fly   332 KLAFLDVKAFERLLGPCMDIMKRNIDDYES 361
            |...||...|||:||.|.||:||||..|.|
Mosquito   338 KCVKLDRARFERVLGLCADILKRNITQYNS 367

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pka-R2	NP_523671.1	DD_RII_PKA	11..46	CDD:438520	9/30 (30%)
		CAP_ED	124..233	CDD:237999	54/108 (50%)
		CAP_ED	242..356	CDD:237999	51/115 (44%)
Pka-R1	XP_001688871.1	DD_RI_PKA	11..59	CDD:438518	11/35 (31%)
		CAP_ED	129..238	CDD:237999	54/108 (50%)
		CAP_ED	247..362	CDD:237999	51/115 (44%)