Protein Alignment Pka-R2 and prkar2a

DIOPT Version :9

• Sequence 1: NP_523671.1
• Gene: Pka-R2 / 36041
• FlyBaseID: FBgn0022382
• Length: 377
• Species: Drosophila melanogaster
• Sequence 2: XP_002933104.1
• Gene: prkar2a / 100486265
• XenbaseID: XB-GENE-982783
• Length: 404
• Species: Xenopus tropicalis
• Alignment Length: 403
• Identity: 189/403 - (46%)
• Similarity: 269/403 - (66%)
• Gaps: 40/403 - (9%)

  Fly     9 IQVPEELKEVLLQFSISFLVEQPPDVIDYAVEYFTKLQ-----------SERP------------ 50
            |::|..|.::|..:::..|.::|||::::|::|||:|:           |.||
 Frog     3 IEIPPGLTDLLQGYTVEVLRQKPPDLVEFAIQYFTRLKEKQLQDGAGAGSLRPHARVVNFDGEPM 67

  Fly    51 -SVSHTDQSTDDQLSVNSQDADAEPPVM-ASSRRKSVFAEAYDPEADDDDDGATAVFPKTDEQRA 113
             :.|:.|:..|::   :..|:|.||||: ..|||.||.||||:|:.:|:|.....|.|||||||.
 Frog    68 QTESNGDEEEDEE---DDDDSDFEPPVINRYSRRVSVCAEAYNPDEEDEDTEPRVVRPKTDEQRC 129

  Fly   114 RLVESVKNVLLFRSLEKEQMNQVLDAMFERKVQPGDFIIRQGDDGDNFYVIESGVYKVYI----N 174
            ||.|:.|::|||::|::||::||||||||.:|:|.:.:|.||||||||||:|.|.|.:::    .
 Frog   130 RLQEACKDILLFKNLDQEQLSQVLDAMFEMRVKPQEHVIDQGDDGDNFYVVERGQYDIFVERDGQ 194

  Fly   175 DKHINTYNHTGLFGELALLYNMPRAATVQAETSGLLWAMDRQTFRRILLKSAFRKRKMYEELLNS 239
            .:.:..|::.|.||||||:||.|||||:.|.:.|.||.:||.|||||:||:..:|||.||..:.|
 Frog   195 SRCVGRYDNHGSFGELALMYNTPRAATIVATSEGALWGLDRVTFRRIILKNNAKKRKTYEIFIES 259

  Fly   240 VPMLKALQNYERMNLADALVSKSYDNGERIIKQGDAADGMYFIEEGTVSVRM-------DQDDAE 297
            ||:||.|:..|||.:.|.:.::.|.:|:|||.|||.||..:.:|.|.|.:.|       .:.:.|
 Frog   260 VPVLKFLELSERMKIVDVIAARVYKDGDRIIAQGDKADCFFIVESGEVKIMMKSKTKTGQESNQE 324

  Fly   298 VEISQLGKGQYFGELALVTHRPRAASVYATGGVVKLAFLDVKAFERLLGPCMDIMKRNIDDYESQ 362
            |||::...|||||||||||::|||||.||.|. ||...:||:|||||||||||||||||..||.|
 Frog   325 VEIARCKSGQYFGELALVTNKPRAASAYAVGD-VKCLIMDVQAFERLLGPCMDIMKRNITHYEEQ 388

  Fly   363 LVKIFGSKNNITD 375
            ||.:|||..::.|
 Frog   389 LVALFGSSMDLRD 401

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pka-R2	NP_523671.1	DD_RII_PKA	11..49	CDD:213046	13/48 (27%)
		CAP_ED	124..233	CDD:237999	60/112 (54%)
		CAP_ED	242..356	CDD:237999	63/120 (53%)
prkar2a	XP_002933104.1	DD_RIIalpha_PKA	3..43	CDD:213050	13/39 (33%)
		CAP_ED	140..253	CDD:237999	60/112 (54%)
		CAP_ED	262..382	CDD:237999	63/120 (53%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	95	1.000	Domainoid score	I7286
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H3064
Inparanoid	1	1.050	356	1.000	Inparanoid score	I2188
OMA	1	1.010	-	-		QHG54324
OrthoDB	1	1.010	-	-		D1047290at2759
OrthoFinder	1	1.000	-	-		FOG0000531
OrthoInspector	1	1.000	-	-		otm48287
Panther	1	1.100	-	-	O	PTHR11635
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2591
SonicParanoid	1	1.000	-	-		X421
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	12.110