DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment TER94 and MSP1

DIOPT Version :9

Sequence 1:	NP_001097249.1	Gene:	TER94 / 36040	FlyBaseID:	FBgn0286784	Length:	826	Species:	Drosophila melanogaster
Sequence 2:	NP_011542.3	Gene:	MSP1 / 852915	SGDID:	S000003260	Length:	362	Species:	Saccharomyces cerevisiae

Alignment Length:	354	Identity:	113/354 - (31%)
Similarity:	173/354 - (48%)	Gaps:	53/354 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   384 RFDRE--IDIGIPDATGRLEVLRIHTKNMKLHDDVDLEQIAAESHGHVGADLASLCSEAALQQIR 446
            :||.:  .|:.:...||    :.::....:|.:||:...::.:|                    |
Yeast     4 KFDLKTITDLSVLVGTG----ISLYYLVSRLLNDVESGPLSGKS--------------------R 44

  Fly   447 EKMDLIDLEDDKIDAEVLASLAVTMENFRYAMTKS--SPSALRETVVEVPNTTWTDIGGLESVKK 509
            |......|:.:|:.....|...||::.:...:..|  :|..:        |.|:.|||||:.:..
Yeast    45 ESKAKQSLQWEKLVKRSPALAEVTLDAYERTILSSIVTPDEI--------NITFQDIGGLDPLIS 101

  Fly   510 ELQELVQYPVEHPDKFLKFG-MQPSRGVLFYGPPGCGKTLLAKAIANECQANFISVKGPELLTMW 573
            :|.|.|.||:..|:.:.... :|...|||.|||||||||:||||:|.|..|||||::...::..|
Yeast   102 DLHESVIYPLMMPEVYSNSPLLQAPSGVLLYGPPGCGKTMLAKALAKESGANFISIRMSSIMDKW 166

  Fly   574 FGESEANVRDIFDKARSAAPCVLFFDELDSIAKARGGNVGDAGGAADRVIN-----QILTEMDGM 633
            :|||...|..:|..|....||::|.||:||..:.|        .:.|..:.     :.:|..||:
Yeast   167 YGESNKIVDAMFSLANKLQPCIIFIDEIDSFLRER--------SSTDHEVTATLKAEFMTLWDGL 223

  Fly   634 GAKKNVFIIGATNRPDIIDPAILRPGRLDQLIYIPLPDDKSREAILKANLRKSPLAK-EVDLTYI 697
            .....|.|||||||.:.||.|.||  ||.:...:.||....|..||...|:.:.|.: |.||..|
Yeast   224 LNNGRVMIIGATNRINDIDDAFLR--RLPKRFLVSLPGSDQRYKILSVLLKDTKLDEDEFDLQLI 286

  Fly   698 AKVTQGFSGADLTEICQRACKLAIRQAIE 726
            |..|:||||:||.|:|:.|...|.::.|:
Yeast   287 ADNTKGFSGSDLKELCREAALDAAKEYIK 315

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
TER94	NP_001097249.1	CDC48	47..787	CDD:273521	113/354 (32%)
		CDC48_N	47..129	CDD:280513
		CDC48_2	153..213	CDD:215011
		AAA	263..392	CDD:278434	3/9 (33%)
		AAA	536..669	CDD:278434	56/137 (41%)
		Vps4_C	<741..783	CDD:286426
MSP1	NP_011542.3	MDN1	<10..>164	CDD:227596	53/185 (29%)
		RecA-like_ATAD1	92..255	CDD:410928	69/172 (40%)
		AAA_lid_3	280..319	CDD:407720	17/36 (47%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0464
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810