DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment TER94 and AtCDC48B

DIOPT Version :9

Sequence 1:	NP_001097249.1	Gene:	TER94 / 36040	FlyBaseID:	FBgn0286784	Length:	826	Species:	Drosophila melanogaster
Sequence 2:	NP_190891.1	Gene:	AtCDC48B / 824489	AraportID:	AT3G53230	Length:	815	Species:	Arabidopsis thaliana

Alignment Length:	810	Identity:	593/810 - (73%)
Similarity:	701/810 - (86%)	Gaps:	12/810 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 DSFDKREDLATAILKRKDRPNRLIVEEAQNDDNSVVSLSQAKMDELQLFRGDTVILKGKRRKETV 90
            ||...::|.:||||::|...|||:|:||.|||||||||....|::||||||||:::|||:||:||
plant     9 DSKGTKKDFSTAILEKKKAANRLVVDEAINDDNSVVSLHPDTMEKLQLFRGDTILIKGKKRKDTV 73

  Fly    91 CIVLSDDTCPDEKIRMNRVVRNNLCVHLSDVVSVQSCPDVKYGKRVRILPIDESTEGVTGNLFEI 155
            ||.|:|:||.:.|||||:|||:||.|.|.||:||..|||||||.||.|||:|::.|||:||:|:.
plant    74 CIALADETCDEPKIRMNKVVRSNLRVRLGDVISVHQCPDVKYGNRVHILPLDDTIEGVSGNIFDA 138

  Fly   156 YLKPYFLEAYRPIHMGDNFIVRAAMRPIEFKVVLTDPEPYCIVAPETVIFCDGDPIKREEEEESL 220
            ||||||||||||:..||.|:||..||.|||||:.|||..||:|||:|.|||:|:|||||:||. |
plant   139 YLKPYFLEAYRPVRKGDLFLVRGGMRSIEFKVIETDPAEYCVVAPDTEIFCEGEPIKREDEER-L 202

  Fly   221 NAVGYDDIGGCRKQLAQIKEMVELPLRHPSLFKAIGVKPPRGILMYGPPGTGKTLIARAVANETG 285
            :.|||||:||.|||:|||:|:||||||||.|||:||||||:|||:|||||:||||||||||||||
plant   203 DEVGYDDVGGVRKQMAQIRELVELPLRHPQLFKSIGVKPPKGILLYGPPGSGKTLIARAVANETG 267

  Fly   286 AFFFLINGPEIMSKLAGESESNLRKAFEEAEKNSPAIIFIDEIDAIAPKRDKTHGEVERRIVSQL 350
            ||||.||||||||||||||||||||||||||||:|:||||||||:|||||:||||||||||||||
plant   268 AFFFCINGPEIMSKLAGESESNLRKAFEEAEKNAPSIIFIDEIDSIAPKREKTHGEVERRIVSQL 332

  Fly   351 LTLMDGMKKSSHLIVMAATNRPNSIDPALRRFGRFDREIDIGIPDATGRLEVLRIHTKNMKLHDD 415
            ||||||:|..:|:|||.|||||||||||||||||||||||||:||..|||||||||||||||.:|
plant   333 LTLMDGLKSRAHVIVMGATNRPNSIDPALRRFGRFDREIDIGVPDEIGRLEVLRIHTKNMKLAED 397

  Fly   416 VDLEQIAAESHGHVGADLASLCSEAALQQIREKMDLIDLEDDKIDAEVLASLAVTMENFRYAMTK 480
            ||||:::.::||:||||||:||:|||||.||||||:|||:|::||||:|.|:||:.::|:.|:..
plant   398 VDLERVSKDTHGYVGADLAALCTEAALQCIREKMDVIDLDDEEIDAEILNSMAVSNDHFQTALGN 462

  Fly   481 SSPSALRETVVEVPNTTWTDIGGLESVKKELQELVQYPVEHPDKFLKFGMQPSRGVLFYGPPGCG 545
            |:|||||||||||||.:|.||||||:||:||||.||||||||:||.||||.||:|||||||||||
plant   463 SNPSALRETVVEVPNVSWEDIGGLENVKRELQETVQYPVEHPEKFEKFGMSPSKGVLFYGPPGCG 527

  Fly   546 KTLLAKAIANECQANFISVKGPELLTMWFGESEANVRDIFDKARSAAPCVLFFDELDSIAKARGG 610
            ||||||||||||||||||:||||||||||||||||||:||||||.:||||||||||||||..||.
plant   528 KTLLAKAIANECQANFISIKGPELLTMWFGESEANVREIFDKARQSAPCVLFFDELDSIATQRGN 592

  Fly   611 NVGDAGGAADRVINQILTEMDGMGAKKNVFIIGATNRPDIIDPAILRPGRLDQLIYIPLPDDKSR 675
            :|||||||||||:||:|||||||.|||.||||||||||||||||:||||||||||||||||::||
plant   593 SVGDAGGAADRVLNQLLTEMDGMNAKKTVFIIGATNRPDIIDPALLRPGRLDQLIYIPLPDEESR 657

  Fly   676 EAILKANLRKSPLAKEVDLTYIAKVTQGFSGADLTEICQRACKLAIRQAIEAEIRREKERAENQN 740
            ..|.|:.|||||:||:|||..:||.||||||||:||||||:||.|||:.||.:|.:|::|||:.
plant   658 YQIFKSCLRKSPVAKDVDLRALAKYTQGFSGADITEICQRSCKYAIRENIEKDIEKERKRAESP- 721

  Fly   741 SAMDMDEDDPVPEITSAHFEEAMKFARRSVSDNDIRKYEMFAQTLQQSRGFGQNFRFP----GQT 801
            .||:.||:: :.||.:.||||:||:|||||||.|||||:.||||||||||||..||||    |.|
plant   722 EAMEEDEEE-IAEIKAGHFEESMKYARRSVSDADIRKYQAFAQTLQQSRGFGSEFRFPDAPTGTT 785

  Fly   802 GNTSGS-----GNNLPVNSPGDNGDDDLYS 826
            |...|:     |.:....|.|...||||||
plant   786 GAFPGAAATVGGVDPFATSGGAADDDDLYS 815

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
TER94	NP_001097249.1	CDC48	47..787	CDD:273521	560/739 (76%)
		CDC48_N	47..129	CDD:280513	53/81 (65%)
		CDC48_2	153..213	CDD:215011	40/59 (68%)
		AAA	263..392	CDD:278434	115/128 (90%)
		AAA	536..669	CDD:278434	119/132 (90%)
		Vps4_C	<741..783	CDD:286426	25/41 (61%)
AtCDC48B	NP_190891.1	CDC48	30..767	CDD:273521	560/739 (76%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	252	1.000	Domainoid score	I518
eggNOG	1	0.900	-	-		E1_COG0464
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5168
Inparanoid	1	1.050	1186	1.000	Inparanoid score	I21
OMA	1	1.010	-	-		QHG60945
OrthoDB	1	1.010	-	-		D194195at2759
OrthoFinder	1	1.000	-	-		FOG0000137
OrthoInspector	1	1.000	-	-		otm2966
orthoMCL	1	0.900	-	-		OOG6_100525
Panther	1	1.100	-	-	O	PTHR23077
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1760
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840