DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment TER94 and CDC48

DIOPT Version :9

Sequence 1:	NP_001097249.1	Gene:	TER94 / 36040	FlyBaseID:	FBgn0286784	Length:	826	Species:	Drosophila melanogaster
Sequence 2:	NP_187595.1	Gene:	CDC48 / 820142	AraportID:	AT3G09840	Length:	809	Species:	Arabidopsis thaliana

Alignment Length:	814	Identity:	604/814 - (74%)
Similarity:	699/814 - (85%)	Gaps:	19/814 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 PKDSFD--KREDLATAILKRKDRPNRLIVEEAQNDDNSVVSLSQAKMDELQLFRGDTVILKGKRR 86
            |.:|.|  .::|.:||||:||..||||:|:||.|||||||||..|.|::||||||||:::|||:|
plant     4 PAESSDSKSKKDFSTAILERKKSPNRLVVDEAINDDNSVVSLHPATMEKLQLFRGDTILIKGKKR 68

  Fly    87 KETVCIVLSDDTCPDEKIRMNRVVRNNLCVHLSDVVSVQSCPDVKYGKRVRILPIDESTEGVTGN 151
            |:||||.|:|:||.:.|||||:|||:||.|.|.||:||..||||||||||.|||:|::.||||||
plant    69 KDTVCIALADETCEEPKIRMNKVVRSNLRVRLGDVISVHQCPDVKYGKRVHILPVDDTVEGVTGN 133

  Fly   152 LFEIYLKPYFLEAYRPIHMGDNFIVRAAMRPIEFKVVLTDPEPYCIVAPETVIFCDGDPIKREEE 216
            ||:.||||||||||||:..||.|:||..||.:||||:.|||..||:|||:|.|||:|:|:|||:|
plant   134 LFDAYLKPYFLEAYRPVRKGDLFLVRGGMRSVEFKVIETDPAEYCVVAPDTEIFCEGEPVKREDE 198

  Fly   217 EESLNAVGYDDIGGCRKQLAQIKEMVELPLRHPSLFKAIGVKPPRGILMYGPPGTGKTLIARAVA 281
            |. |:.|||||:||.|||:|||:|:||||||||.|||:||||||:|||:|||||:||||||||||
plant   199 ER-LDDVGYDDVGGVRKQMAQIRELVELPLRHPQLFKSIGVKPPKGILLYGPPGSGKTLIARAVA 262

  Fly   282 NETGAFFFLINGPEIMSKLAGESESNLRKAFEEAEKNSPAIIFIDEIDAIAPKRDKTHGEVERRI 346
            ||||||||.||||||||||||||||||||||||||||:|:||||||||:|||||:||:|||||||
plant   263 NETGAFFFCINGPEIMSKLAGESESNLRKAFEEAEKNAPSIIFIDEIDSIAPKREKTNGEVERRI 327

  Fly   347 VSQLLTLMDGMKKSSHLIVMAATNRPNSIDPALRRFGRFDREIDIGIPDATGRLEVLRIHTKNMK 411
            ||||||||||:|..:|:|||.|||||||||||||||||||||||||:||..||||||||||||||
plant   328 VSQLLTLMDGLKSRAHVIVMGATNRPNSIDPALRRFGRFDREIDIGVPDEIGRLEVLRIHTKNMK 392

  Fly   412 LHDDVDLEQIAAESHGHVGADLASLCSEAALQQIREKMDLIDLEDDKIDAEVLASLAVTMENFRY 476
            |.:|||||:|:.::||:||||||:||:|||||.||||||:||||||.||||:|.|:|||.|:|..
plant   393 LAEDVDLERISKDTHGYVGADLAALCTEAALQCIREKMDVIDLEDDSIDAEILNSMAVTNEHFHT 457

  Fly   477 AMTKSSPSALRETVVEVPNTTWTDIGGLESVKKELQELVQYPVEHPDKFLKFGMQPSRGVLFYGP 541
            |:..|:|||||||||||||.:|.||||||:||:||||.||||||||:||.||||.||:|||||||
plant   458 ALGNSNPSALRETVVEVPNVSWNDIGGLENVKRELQETVQYPVEHPEKFEKFGMSPSKGVLFYGP 522

  Fly   542 PGCGKTLLAKAIANECQANFISVKGPELLTMWFGESEANVRDIFDKARSAAPCVLFFDELDSIAK 606
            |||||||||||||||||||||||||||||||||||||||||:||||||.:||||||||||||||.
plant   523 PGCGKTLLAKAIANECQANFISVKGPELLTMWFGESEANVREIFDKARQSAPCVLFFDELDSIAT 587

  Fly   607 AR-GGNVGDAGGAADRVINQILTEMDGMGAKKNVFIIGATNRPDIIDPAILRPGRLDQLIYIPLP 670
            .| ||:.||.|||||||:||:|||||||.|||.||||||||||||||.|:|||||||||||||||
plant   588 QRGGGSGGDGGGAADRVLNQLLTEMDGMNAKKTVFIIGATNRPDIIDSALLRPGRLDQLIYIPLP 652

  Fly   671 DDKSREAILKANLRKSPLAKEVDLTYIAKVTQGFSGADLTEICQRACKLAIRQAIEAEIRREKER 735
            |:.||..|.||.|||||:||:||:..:||.||||||||:|||||||||.|||:.||.:|.:||.|
plant   653 DEDSRLNIFKAALRKSPIAKDVDIGALAKYTQGFSGADITEICQRACKYAIRENIEKDIEKEKRR 717

  Fly   736 AENQNSAMDMDEDDPVPEITSAHFEEAMKFARRSVSDNDIRKYEMFAQTLQQSRGFGQNFRFPGQ 800
            :||. .||:.|..|.|.||.:|||||:||:|||||||.|||||:.||||||||||||..|||.
plant   718 SENP-EAMEEDGVDEVSEIKAAHFEESMKYARRSVSDADIRKYQAFAQTLQQSRGFGSEFRFE-- 779

  Fly   801 TGNTSGSGNNLPVNSP--------GDNGDDDLYS 826
              |::|||....|..|        ||  |||||:
plant   780 --NSAGSGATTGVADPFATSAAAAGD--DDDLYN 809

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
TER94	NP_001097249.1	CDC48	47..787	CDD:273521	569/740 (77%)
		CDC48_N	47..129	CDD:280513	54/81 (67%)
		CDC48_2	153..213	CDD:215011	38/59 (64%)
		AAA	263..392	CDD:278434	114/128 (89%)
		AAA	536..669	CDD:278434	118/133 (89%)
		Vps4_C	<741..783	CDD:286426	27/41 (66%)
CDC48	NP_187595.1	CDC48	29..768	CDD:273521	569/740 (77%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	252	1.000	Domainoid score	I518
eggNOG	1	0.900	-	-		E1_COG0464
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5168
Inparanoid	1	1.050	1186	1.000	Inparanoid score	I21
OMA	1	1.010	-	-		QHG60945
OrthoDB	1	1.010	-	-		D194195at2759
OrthoFinder	1	1.000	-	-		FOG0000137
OrthoInspector	1	1.000	-	-		otm2966
orthoMCL	1	0.900	-	-		OOG6_100525
Panther	1	1.100	-	-	O	PTHR23077
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1760
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840