DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment TER94 and CDC48B

DIOPT Version :9

Sequence 1:	NP_001097249.1	Gene:	TER94 / 36040	FlyBaseID:	FBgn0286784	Length:	826	Species:	Drosophila melanogaster
Sequence 2:	NP_178463.1	Gene:	CDC48B / 814895	AraportID:	AT2G03670	Length:	603	Species:	Arabidopsis thaliana

Alignment Length:	590	Identity:	226/590 - (38%)
Similarity:	349/590 - (59%)	Gaps:	56/590 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   215 EEEESL--NAVGYD------DIGGCRKQLAQIKEMVELPLRHPSLFKAIGVKPPRGILMYGPPGT 271
            |.|.|:  |..|.:      :|||..:.|..::|::..|.|:|...:.:|:|.|||:|:||||||
plant     3 ETESSVCDNIAGNEKWRAEAEIGGNERALQALRELIIFPFRYPLEARTLGLKWPRGLLLYGPPGT 67

  Fly   272 GKTLIARAVANETGAFFFLINGPEIMSKLAGESESNLRKAFEEAEKNS----PAIIFIDEIDAIA 332
            |||.:.|||..|..|...:::...:....|||||..||:||.||..::    |::|||||||.:.
plant    68 GKTSLVRAVVQECDAHLIVLSPHSVHRAHAGESEKVLREAFAEASSHAVSDKPSVIFIDEIDVLC 132

  Fly   333 PKRDKTHGEVERRIVSQLLTLMDGMKKSS---HLIVMAATNRPNSIDPALRRFGRFDREIDIGIP 394
            |:|| ...|.:.||.|||.||||..|.||   .::|:|:|||.::|||||||.||||..:::..|
plant   133 PRRD-ARREQDVRIASQLFTLMDSNKPSSSAPRVVVVASTNRVDAIDPALRRAGRFDALVEVSTP 196

  Fly   395 DATGRLEVLRIHTKNMKLHDDVDLEQIAAESHGHVGADLASLCSEAALQQIREKMDLIDLEDDKI 459
            :...||::|:::||.:.|...|||:.||...:|:|||||.:||.||.:...:...|
plant   197 NEEDRLKILQLYTKKVNLDPSVDLQAIAISCNGYVGADLEALCREATISASKRSSD--------- 252

  Fly   460 DAEVLASLAVTMENFRYAMTKSSPSALRETVVEVPNTTWTDIGGLESVKKELQELVQYPVEHPDK 524
                  ||.:|.::|:.|.:...||..|...||:|..||.|:|||:.:||:||:.|::|::|...
plant   253 ------SLILTSQDFKIAKSVVGPSINRGITVEIPKVTWDDVGGLKDLKKKLQQAVEWPIKHSAA 311

  Fly   525 FLKFGMQPSRGVLFYGPPGCGKTLLAKAIANECQANFISVKGPELLTMWFGESEANVRDIFDKAR 589
            |:|.|:.|.||:|.:|||||.||.||||.||..||:|.|:...||.:|:.||.||.:|:.|.:||
plant   312 FVKMGISPMRGILLHGPPGCSKTTLAKAAANAAQASFFSLSCAELFSMYVGEGEALLRNTFQRAR 376

  Fly   590 SAAPCVLFFDELDSIAKARGG-NVGDAGGAADRVINQILTEMDGMGAKKNVFIIGATNRPDIIDP 653
            .|:|.::||||.|.:|..||. :..::....:|:::.:||||||:...|.:.::.|||||..||.
plant   377 LASPSIIFFDEADVVACKRGDESSSNSSTVGERLLSTLLTEMDGLEEAKGILVLAATNRPYAIDA 441

  Fly   654 AILRPGRLDQLIYIPLPDDKSREAILKANLRKSPLAKEVDLTYIAKVTQGFSGADLTEICQRACK 718
            |::||||.|.::|:|.||.::|..||:.:.|...|..:|||..||:.|..|:||:|..:|:.:..
plant   442 ALMRPGRFDLVLYVPPPDLEARFEILQVHTRNMTLGDDVDLRKIAEETDLFTGAELEGLCRESGT 506

  Fly   719 LAIRQAIEAEIRREKERAENQNSAMDMDEDDPVPEITSAHFEEAMKFARRSVSDNDIRKYEMFAQ 783
            :::|:.|.|                        ..:.:.||:.|....:.:::..::..|..|.:
plant   507 VSLRENIAA------------------------TAVFNRHFQTAKSSLKPALTIEEVETYSSFRK 547

  Fly   784 TLQQS 788
            ..::|
plant   548 AAKRS 552

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
TER94	NP_001097249.1	CDC48	47..787	CDD:273521	225/587 (38%)
		CDC48_N	47..129	CDD:280513
		CDC48_2	153..213	CDD:215011
		AAA	263..392	CDD:278434	66/135 (49%)
		AAA	536..669	CDD:278434	61/133 (46%)
		Vps4_C	<741..783	CDD:286426	5/41 (12%)
CDC48B	NP_178463.1	CDC48	<23..551	CDD:273521	220/567 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0464
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D194195at2759
OrthoFinder	1	1.000	-	-		FOG0000137
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820