DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment TER94 and Fign

DIOPT Version :9

Sequence 1:	NP_001097249.1	Gene:	TER94 / 36040	FlyBaseID:	FBgn0286784	Length:	826	Species:	Drosophila melanogaster
Sequence 2:	NP_068362.1	Gene:	Fign / 60344	MGIID:	1890647	Length:	759	Species:	Mus musculus

Alignment Length:	573	Identity:	134/573 - (23%)
Similarity:	219/573 - (38%)	Gaps:	128/573 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   249 PSLFKAIGVK-----PPRGILMYGPPGTGKTLIA-RAVANETGAFF----FLINGPEIMSKLAGE 303
            ||.:...|:.     ||..:..|...|.|.|.|| .|:.|.:.:..    |.:.|...|....|.
Mouse   271 PSAYLPSGIPAPTPLPPTTVPGYTYQGHGLTPIAPSALTNNSASSLKRKAFYMAGQGDMDSSYGN 335

  Fly   304 ---------------------SESNLRKAFEEAEKNSPAIIFIDEIDAIAPKRDKTHGEVERRIV 347
                                 |.||....|:...:.|..        |..|.:.....|.:|:..
Mouse   336 YSYGQQRSTQSPMYRMPDNSISNSNRGNGFDRNAETSSL--------AFKPTKQLMPSEQQRKFS 392

  Fly   348 SQLLTLMDGMKKSSHLIVMAATNRPNSI-DPALRRFGRFDREIDIGIPDATGRLEVLRIHTKNMK 411
            ||         .|..|...:.:...||: ..:...||::...:                    |.
Mouse   393 SQ---------SSRALTPPSYSTAKNSLGSRSSESFGKYTSPV--------------------MS 428

  Fly   412 LHDDVDLEQIAAESHGHVGADLASLCSEAALQQIRE-KMDLIDLEDDKIDAEVLASLAVTMENFR 475
            .|.| |..|:.|......|...|:..:.:..:|::. ...||||              ||
Mouse   429 EHGD-DHRQLLAHPIQGPGLRAATSSNHSVDEQLKNTDTHLIDL--------------VT----- 473

  Fly   476 YAMTKSSPSALRETVVEVPNTTWTDIGGLESVKKELQELVQYPVEHPDKFLKFGMQPSRGVLFYG 540
                       .|.:.:.|...|:||.||:.||..::|.|.:||...|.|......| |.:|.:|
Mouse   474 -----------NEIITQGPPVDWSDIAGLDLVKAVIKEEVLWPVLRSDAFSGLTALP-RSILLFG 526

  Fly   541 PPGCGKTLLAKAIANECQANFISVKGPELLTMWFGESEANVRDIFDKARSAAPCVLFFDELDSIA 605
            |.|.|||||.:.||::..|.|..:.|..|:..|.||:|..:...|..||...|.|:|..::|.:.
Mouse   527 PRGTGKTLLGRCIASQLGATFFKIAGSGLVAKWIGEAEKIIHASFLVARCRQPSVIFVSDIDMLL 591

  Fly   606 KARGGNVGDAGGAADRVINQILTEMDGM--GAKKNVFIIGATNRPDIIDPAILRPGRLDQLIYIP 668
            .::   |.:......|:..:.|.::|.:  .|:..:.:|.||::|:.||.::.|  ...:.:.||
Mouse   592 SSQ---VSEEHSPVSRMRTEFLMQLDTVLTSAEDQIVVICATSKPEEIDESLRR--YFMKRLLIP 651

  Fly   669 LPDDKSREAILKANL-RKSPLAKEVDLTYIAKVTQGFSGADLTEICQRACKLAIRQAIEAEIRRE 732
            |||..:|..|:...| :.:....:.:...:.:.|:||||.|:..:||.|....:......::
Mouse   652 LPDSTARHQIIVQLLTQHNYCLNDKEFALLVQRTEGFSGLDVAHLCQEAAVGPLHAMPATDL--- 713

  Fly   733 KERAENQNSAMDMDEDDPVPEITSAHFEEAMKFARRSVSDNDIRKY----EMF 781
                    ||:...:..||   |...||.|....:.|:|..::..|    :||
Mouse   714 --------SAIMPSQLRPV---TYQDFENAFCKIQPSISQKELDMYVEWNKMF 755

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
TER94	NP_001097249.1	CDC48	47..787	CDD:273521	134/573 (23%)
		CDC48_N	47..129	CDD:280513
		CDC48_2	153..213	CDD:215011
		AAA	263..392	CDD:278434	29/155 (19%)
		AAA	536..669	CDD:278434	39/134 (29%)
		Vps4_C	<741..783	CDD:286426	13/45 (29%)
Fign	NP_068362.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	89..111
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	200..237
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	258..293		5/21 (24%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	337..429		18/128 (14%)
		26Sp45	389..736	CDD:130309	104/426 (24%)
		AAA	522..652	CDD:278434	39/134 (29%)
		Vps4_C	<723..756	CDD:286426	11/36 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0464
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810