Protein Alignment TER94 and FIGN

DIOPT Version :10

• Sequence 1: NP_001097249.1
• Gene: TER94 / 36040
• FlyBaseID: FBgn0286784
• Length: 826
• Species: Drosophila melanogaster
• Sequence 2: XP_047300819.1
• Gene: FIGN / 55137
• HGNCID: 13285
• Length: 785
• Species: Homo sapiens
• Alignment Length: 575
• Identity: 136/575 - (23%)
• Similarity: 221/575 - (38%)
• Gaps: 132/575 - (22%)

  Fly   249 PSLFKAIGVK-----PPRGILMYGPPGTGKTLIA-RAVANETG------AFFFLING-------- 293
            ||.:...|:.     ||..:..|...|.|.|.|| .|:.|.:.      ||:....|
Human   297 PSAYLPSGIPAPTPLPPTTVPGYTYQGHGLTPIAPSALTNSSASSLKRKAFYMAGQGDMDSSYGN 361

  Fly   294 ---------PEIMSKLAGESESNLRK--AFEEAEKNSPAIIFIDEIDAIAPKRDKTHGEVERRIV 347
                     ...|.::...|.||..:  .|:.:.:.|..        |..|.:.....|.:|:..
Human   362 YSYGQQRSTQSPMYRMPDNSISNTNRGNGFDRSAETSSL--------AFKPTKQLMSSEQQRKFS 418

  Fly   348 SQLLTLMDGMKKSSHLIVMAATNRPNSI-DPALRRFGRFDREIDIGIPDATGRLEVLRIHTKNMK 411
            ||         .|..|...:.:...||: ..:...||::...:                    |.
Human   419 SQ---------SSRALTPPSYSTAKNSLGSRSSESFGKYTSPV--------------------MS 454

  Fly   412 LHDDVDLEQIAAESHGHVGADL-ASLCSEAALQQIREKMD--LIDLEDDKIDAEVLASLAVTMEN 473
            .|.|   |.....||...|..| |:..|..::.:..:..|  ||||              ||
Human   455 EHGD---EHRQLLSHPMQGPGLRAATSSNHSVDEQLKNTDTHLIDL--------------VT--- 499

  Fly   474 FRYAMTKSSPSALRETVVEVPNTTWTDIGGLESVKKELQELVQYPVEHPDKFLKFGMQPSRGVLF 538
                         .|.:.:.|...|.||.||:.||..::|.|.:||...|.|......| |.:|.
Human   500 -------------NEIITQGPPVDWNDIAGLDLVKAVIKEEVLWPVLRSDAFSGLTALP-RSILL 550

  Fly   539 YGPPGCGKTLLAKAIANECQANFISVKGPELLTMWFGESEANVRDIFDKARSAAPCVLFFDELDS 603
            :||.|.|||||.:.||::..|.|..:.|..|:..|.||:|..:...|..||...|.|:|..::|.
Human   551 FGPRGTGKTLLGRCIASQLGATFFKIAGSGLVAKWLGEAEKIIHASFLVARCRQPSVIFVSDIDM 615

  Fly   604 IAKARGGNVGDAGGAADRVINQILTEMDGM--GAKKNVFIIGATNRPDIIDPAILRPGRLDQLIY 666
            :..::   |.:......|:..:.|.::|.:  .|:..:.:|.||::|:.||.::.|  ...:.:.
Human   616 LLSSQ---VNEEHSPVSRMRTEFLMQLDTVLTSAEDQIVVICATSKPEEIDESLRR--YFMKRLL 675

  Fly   667 IPLPDDKSREAILKANL-RKSPLAKEVDLTYIAKVTQGFSGADLTEICQRACKLAIRQAIEAEIR 730
            |||||..:|..|:...| :.:....:.:...:.:.|:||||.|:..:||.|....:......::
Human   676 IPLPDSTARHQIIVQLLSQHNYCLNDKEFALLVQRTEGFSGLDVAHLCQEAVVGPLHAMPATDL- 739

  Fly   731 REKERAENQNSAMDMDEDDPVPEITSAHFEEAMKFARRSVSDNDIRKY----EMF 781
                      ||:...:..||   |...||.|....:.|:|..::..|    :||
Human   740 ----------SAIMPSQLRPV---TYQDFENAFCKIQPSISQKELDMYVEWNKMF 781

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TER94	NP_001097249.1	CDC48	47..787	CDD:273521	136/575 (24%)
FIGN	XP_047300819.1	RecA-like_fidgetin	513..676	CDD:410931	52/168 (31%)
		AAA_lid_3	701..>732	CDD:465537	9/30 (30%)
		Vps4_C	<749..782	CDD:462762	11/36 (31%)