Protein Alignment TER94 and ATAD2B

DIOPT Version :10

• Sequence 1: NP_001097249.1
• Gene: TER94 / 36040
• FlyBaseID: FBgn0286784
• Length: 826
• Species: Drosophila melanogaster
• Sequence 2: XP_047300755.1
• Gene: ATAD2B / 54454
• HGNCID: 29230
• Length: 1522
• Species: Homo sapiens
• Alignment Length: 810
• Identity: 208/810 - (25%)
• Similarity: 342/810 - (42%)
• Gaps: 188/810 - (23%)

  Fly    15 HSEQDEKMKPKDSFDKREDLATAILKRKDRPNRLIVEEAQNDDNS-VVSLSQAKMDELQLFRGDT 78
            |.|...:.:.::|.::..|:.              ||||:.::|. ..:|.|.|  .:..::...
Human   251 HHEVSTEGEEEESQEEDGDIE--------------VEEAEGEENDRPYNLRQRK--TVDRYQAPP 299

  Fly    79 VILKGKRRKETVCIVLSDDTCPDEKIRMNRVVRNNLCVHLSDVVSVQSCPDVKYGKRV------- 136
            ::...::::|.....:.....     |.:.:.|....:|.||..   |..:.::.:|.
Human   300 IVPAHQKKRENTLFDIHRSPA-----RRSHIRRKKHAIHSSDTT---SSDEERFERRKSKSMARA 356

  Fly   137 --RILPIDESTEGVTGNLFEIYLKPYFLEAYRPIHMGDNFIVRAAMRPIEFKVVLTDPEPYCIVA 199
              |.||::...|.:...:....:|                 |.|::
Human   357 RNRCLPMNFRAEDLASGILRERVK-----------------VGASL------------------- 385

  Fly   200 PETVIFCDGDPIKREEEEESLNAVGYDDIGGCRKQLAQIKEMVELPLRHPSLFKAIGVKPPRGIL 264
                  .|.||:..::      :|.:|.|||....:..:||||..||.:|.:|:...::||||.|
Human   386 ------ADVDPMNIDK------SVRFDSIGGLSHHIHALKEMVVFPLLYPEIFEKFKIQPPRGCL 438

  Fly   265 MYGPPGTGKTLIARAVANETG-----AFFFLINGPEIMSKLAGESESNLRKAFEEAEKNSPAIIF 324
            .||||||||||:|||:|||..     ..||:..|.:.:||..||||..||..|::|....|:|||
Human   439 FYGPPGTGKTLVARALANECSQGDKKVAFFMRKGADCLSKWVGESERQLRLLFDQAYLMRPSIIF 503

  Fly   325 IDEIDAIAPKRDKTHGEVERRIVSQLLTLMDGMKKSSHLIVMAATNRPNSIDPALRRFGRFDREI 389
            .||||.:||.|.....::...|||.||.||||:.....::|:.||||.:||||||||.||||||.
Human   504 FDEIDGLAPVRSSRQDQIHSSIVSTLLALMDGLDNRGEIVVIGATNRLDSIDPALRRPGRFDREF 568

  Fly   390 DIGIPDATGRLEVLRIHTK--NMKLHDDVDLEQIAAESHGHVGADLASLCSEAALQQIREKMDLI 452
            ...:||...|..:|:|||:  |.|| .|..|.::|.:..|:.|||:.:||:||||..:|.:...|
Human   569 LFNLPDQKARKHILQIHTRDWNPKL-SDAFLGELAEKCVGYCGADIKALCTEAALIALRRRYPQI 632

  Fly   453 DLEDDKIDAEVLASLAVTMENFRYAMTKSSPSALR---------------------ETVVEVPNT 496
            .....|:..:| :|:.::.::|.:||....|::.|                     ..::.|...
Human   633 YASSHKLQLDV-SSIVLSAQDFYHAMQNIVPASQRAVMSSGHALSPIIRPLLERSFNNILAVLQK 696

  Fly   497 TWTDIGGLESVKKE-LQELVQYPVE---------------HPDK----------FLKFGMQPSR- 534
            .:......:|.||| ::.|:....|               .|.|          :|.|.|.|..
Human   697 VFPHAEISQSDKKEDIETLILEDSEDENALSIFETNCHSGSPKKQSSSAAIHKPYLHFTMSPYHQ 761

  Fly   535 ------GVLFYGPPGCGKTL-LAKAIANECQANFISVKG---PELLTMWFGESEANVRDIFDKAR 589
                  .:|..|..|.|:|. ||.|:.:..:.  .||..   |.|.::.....|.:...||.:||
Human   762 PTSYRPRLLLSGERGSGQTSHLAPALLHTLER--FSVHRLDLPALYSVSAKTPEESCAQIFREAR 824

  Fly   590 SAAPCVLFFDELDSIAKARGGNVGDAGGAADRVIN-QILTEMDGMGAKKNVFIIGATNR-----P 648
            ...|.:::..           ::||...|....:. ..||.:..:.:...:|::..:..     |
Human   825 RTVPSIVYMP-----------HIGDWWEAVSETVRATFLTLLQDIPSFSPIFLLSTSETMYSELP 878

  Fly   649 DIIDPAILRPGRLDQLIYI--PLPDDKSR---EAILKANLRKSPLAKEVDLTYIAKVTQGFSGAD 708
            :.: ..|.|. :.::::||  |:.:|:.:   |.||.......|..|...|..:
Human   879 EEV-KCIFRI-QYEEVLYIQRPIEEDRRKFFQELILNQASMAPPRRKHAALCAM----------- 930

  Fly   709 LTEICQRACKLAIRQAIEAEIRREKERAEN 738
              |:...|.....||..|:|..|.:::.||
Human   931 --EVLPLALPSPPRQLSESEKSRMEDQEEN 958

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TER94	NP_001097249.1	CDC48	47..787	CDD:273521	204/778 (26%)
ATAD2B	XP_047300755.1	RecA-like_Yta7-like	401..570	CDD:410925	84/168 (50%)
		AAA_lid_3	595..635	CDD:465537	15/39 (38%)
		P-loop containing Nucleoside Triphosphate Hydrolases	759..895	CDD:476819	27/150 (18%)
		COG5076	852..>1081	CDD:227408	25/122 (20%)
		Bromo_AAA	960..1066	CDD:99957