Protein Alignment TER94 and NVL

DIOPT Version :10

• Sequence 1: NP_001097249.1
• Gene: TER94 / 36040
• FlyBaseID: FBgn0286784
• Length: 826
• Species: Drosophila melanogaster
• Sequence 2: XP_016856867.1
• Gene: NVL / 4931
• HGNCID: 8070
• Length: 917
• Species: Homo sapiens
• Alignment Length: 860
• Identity: 294/860 - (34%)
• Similarity: 426/860 - (49%)
• Gaps: 223/860 - (25%)

  Fly     8 RDFMRGYHSEQDEKMKPKDSFDKREDLATAILKRKDRPNRLIVEEAQNDDNSVVSLSQAKMDELQ 72
            :|...|:..::...:| ||||..  ||:.    .|..|.:.|.|...:.|:|::.....:..:|:
Human   201 KDSEGGWFIDKTPSVK-KDSFFL--DLSC----EKSNPKKPITEIQDSKDSSLLESDMKRKGKLK 258

  Fly    73 LFRGDTVILKGKRRKETVCIVLSDDTCPDEKIRMNRVVRNNLCVHLSDVVSVQSCPDVKYGKRVR 137
                    .||.:||:
Human   259 --------NKGSKRKK------------------------------------------------- 266

  Fly   138 ILPIDESTEGVTGNLFEIYLKPYFLEAYRPIHMGDNFIVRAAMRPIEFKVVLTDPEPYCIVAPET 202
                 |..:.|.|.:..:..|                  :|..|.:||::
Human   267 -----EDLQEVDGEIEAVLQK------------------KAKARGLEFQI--------------- 293

  Fly   203 VIFCDGDPIKREEEEESLNAVGYDDIGGCRKQLAQIKEMVELPLRHPSLFKAIGVKPPRGILMYG 267
                              :.|.::|:||....|.::.:|: :.:|||.::..:||.||||:|::|
Human   294 ------------------SNVKFEDVGGNDMTLKEVCKML-IHMRHPEVYHHLGVVPPRGVLLHG 339

  Fly   268 PPGTGKTLIARAVANE------TGAFFFLING---------------------PEIMSKLAGESE 305
            |||.||||:|.|:|..      |....|..:|                     |||:|.::||||
Human   340 PPGCGKTLLAHAIAGAECSGMITAHCSFDFSGSNDPPASASQELDLPILKVAAPEIVSGVSGESE 404

  Fly   306 SNLRKAFEEAEKNSPAIIFIDEIDAIAPKRDKTHGEVERRIVSQLLTLMDGMKK---SSHLIVMA 367
            ..||:.||:|..|:|.||||||||||.|||:....::|||||:||||.||.:..   ::.::|:.
Human   405 QKLRELFEQAVSNAPCIIFIDEIDAITPKREVASKDMERRIVAQLLTCMDDLNNVAATARVLVIG 469

  Fly   368 ATNRPNSIDPALRRFGRFDREIDIGIPDATGRLEVLRIHTKNMKLHDDVDLEQIAAESHGHVGAD 432
            |||||:|:||||||.|||||||.:||||...|..:|:...:.::|....|...:|..:.|.||||
Human   470 ATNRPDSLDPALRRAGRFDREICLGIPDEASRERILQTLCRKLRLPQAFDFCHLAHLTPGFVGAD 534

  Fly   433 LASLCSEAAL-----------QQIREKMDLIDL------------------------------ED 456
            |.:||.|||:           :|.::..::.||                              :.
Human   535 LMALCREAAMCAVNRVLMKLQEQQKKNPEMEDLPSKGVQEERLGTEPTSETQDELQRLLGLLRDQ 599

  Fly   457 DKIDAEVLASLAVTMENFRYAMTKSSPSALRETVVEVPNTTWTDIGGLESVKKELQELVQYPVEH 521
            |.:..|.:..|.:.:.:|..|::...|||.||..|.|||.||.|||.||.:::||...:..||.:
Human   600 DPLSEEQMQGLCIELNDFIVALSSVQPSAKREGFVTVPNVTWADIGALEDIREELTMAILAPVRN 664

  Fly   522 PDKFLKFGMQPSRGVLFYGPPGCGKTLLAKAIANECQANFISVKGPELLTMWFGESEANVRDIFD 586
            ||:|...|:....|||..|||||||||||||:|||...|||||||||||.|:.||||..||.:|.
Human   665 PDQFKALGLVTPAGVLLAGPPGCGKTLLAKAVANESGLNFISVKGPELLNMYVGESERAVRQVFQ 729

  Fly   587 KARSAAPCVLFFDELDSIAKARGGNVGDAGGAADRVINQILTEMDGMGAKKNVFIIGATNRPDII 651
            :|:::||||:||||:|::...|...   ..||:.||:||:||||||:.|::.|||:.||||||||
Human   730 RAKNSAPCVIFFDEVDALCPRRSDR---ETGASVRVVNQLLTEMDGLEARQQVFIMAATNRPDII 791

  Fly   652 DPAILRPGRLDQLIYIPLPDDKSREAILKA---NLRKSPLAKEVDLTYIAKVTQG------FSGA 707
            |||||||||||:.:::.||....|.||||.   |..|.||..:|:|..||    |      ::||
Human   792 DPAILRPGRLDKTLFVGLPPPADRLAILKTITKNGTKPPLDADVNLEAIA----GDLRCDCYTGA 852

  Fly   708 DLTEICQRACKLAIRQAIEAEIRREKERAENQNSAMDMDEDDPVPEITSAHFEEAMKFARRSVSD 772
            ||:.:.:.|...|:||    |:.|:|  :.|:...:         :::..|||||.|..|.|:|.
Human   853 DLSALVREASICALRQ----EMARQK--SGNEKGEL---------KVSHKHFEEAFKKVRSSISK 902

  Fly   773 NDIRKYEMFAQTLQQ 787
            .|...||...::|.:
Human   903 KDQIMYERLQESLSR 917

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TER94	NP_001097249.1	CDC48	47..787	CDD:273521	283/819 (35%)
NVL	XP_016856867.1	Nucleolin_bd	2..72	CDD:465247
		CDC48	<277..917	CDD:273521	271/713 (38%)