Protein Alignment TER94 and NSF

DIOPT Version :9

• Sequence 1: NP_001097249.1
• Gene: TER94 / 36040
• FlyBaseID: FBgn0286784
• Length: 826
• Species: Drosophila melanogaster
• Sequence 2: NP_006169.2
• Gene: NSF / 4905
• HGNCID: 8016
• Length: 744
• Species: Homo sapiens
• Alignment Length: 556
• Identity: 168/556 - (30%)
• Similarity: 263/556 - (47%)
• Gaps: 112/556 - (20%)

  Fly   216 EEESLNAVGYD-------------------DIGGCRKQLAQI-KEMVELPLRHPSLFKAIGVKPP 260
            |..|||.:|..                   .|||..|:.:.| :......:..|.:.:.:|.|..
Human   189 ENSSLNLIGKAKTKENRQSIINPDWNFEKMGIGGLDKEFSDIFRRAFASRVFPPEIVEQMGCKHV 253

  Fly   261 RGILMYGPPGTGKTLIARAV-----ANETGAFFFLINGPEIMSKLAGESESNLRKAFEEAEK--- 317
            :|||:|||||.||||:||.:     |.|..    ::|||||::|..||||:|:||.|.:||:
Human   254 KGILLYGPPGCGKTLLARQIGKMLNAREPK----VVNGPEILNKYVGESEANIRKLFADAEEEQR 314

  Fly   318 ----NSPA-IIFIDEIDAIAPKRDKTHGE--VERRIVSQLLTLMDGMKKSSHLIVMAATNRPNSI 375
                ||.. ||..||||||..:|....|.  |...:|:|||:.:||:::.::::|:..||||:.|
Human   315 RLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHDTVVNQLLSKIDGVEQLNNILVIGMTNRPDLI 379

  Fly   376 DPALRRFGRFDREIDIGIPDATGRLEVLRIHTKNMKLHD----DVDLEQIAAESHGHVGADLASL 436
            |.||.|.||.:.:::||:||..|||::|.|||..|:.|.    |||::::|.|:....||:|..|
Human   380 DEALLRPGRLEVKMEIGLPDEKGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGL 444

  Fly   437 C----SEAALQQIREKMDLIDLEDDKIDAEVLASLAVTMENFRYAMTKSSPSALRETVVEVPNTT 497
            .    |.|..:.|:....:      ::|.|...||.||..:|.        ::|...:.....|.
Human   445 VRAAQSTAMNRHIKASTKV------EVDMEKAESLQVTRGDFL--------ASLENDIKPAFGTN 495

  Fly   498 WTD-----IGGL----ESVKKELQ--ELVQYPVEHPDKFLKFGMQPSRGVLFYGPPGCGKTLLAK 551
            ..|     :.|:    :.|.:.|.  ||:....::.|:      .|...||..|||..|||.||.
Human   496 QEDYASYIMNGIIKWGDPVTRVLDDGELLVQQTKNSDR------TPLVSVLLEGPPHSGKTALAA 554

  Fly   552 AIANECQANFISVKGPELLTMWFGESEA----NVRDIFDKA-RSAAPCVLFFDELDSIAKARGGN 611
            .||.|....||.:..|:.:   .|.||.    .::.|||.| :|...||: .|:::.:.
Human   555 KIAEESNFPFIKICSPDKM---IGFSETAKCQAMKKIFDDAYKSQLSCVV-VDDIERLL------ 609

  Fly   612 VGDAGGAADRVINQILTEMDGMGAK-----KNVFIIGATNRPDIIDPAILRPGRLDQL----IYI 667
              |......|..|.:|..:..:..|     :.:.|||.|:|.|::.       .::.|    ..|
Human   610 --DYVPIGPRFSNLVLQALLVLLKKAPPQGRKLLIIGTTSRKDVLQ-------EMEMLNAFSTTI 665

  Fly   668 PLPDDKSREAILKANLRKSPLAKEVDLTYIAKVTQG 703
            .:|:..:.|.:|:| |......|:.:.|.||:..:|
Human   666 HVPNIATGEQLLEA-LELLGNFKDKERTTIAQQVKG 700

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TER94	NP_001097249.1	CDC48	47..787	CDD:273521	168/556 (30%)
		CDC48_N	47..129	CDD:280513
		CDC48_2	153..213	CDD:215011
		AAA	263..392	CDD:278434	62/143 (43%)
		AAA	536..669	CDD:278434	40/146 (27%)
		Vps4_C	<741..783	CDD:286426
NSF	NP_006169.2	CDC48_N	6..83	CDD:215012
		CDC48_2	111..>159	CDD:308534
		SpoVK	<142..490	CDD:223540	109/318 (34%)
		AAA	538..670	CDD:214640	41/150 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0464
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810