Protein Alignment TER94 and spas

DIOPT Version :10

• Sequence 1: NP_001097249.1
• Gene: TER94 / 36040
• FlyBaseID: FBgn0286784
• Length: 826
• Species: Drosophila melanogaster
• Sequence 2: NP_651206.3
• Gene: spas / 42846
• FlyBaseID: FBgn0039141
• Length: 758
• Species: Drosophila melanogaster
• Alignment Length: 643
• Identity: 167/643 - (25%)
• Similarity: 271/643 - (42%)
• Gaps: 134/643 - (20%)

  Fly   214 EEEEESLNAVG--YDDIGGCRKQLAQIKEMVELPLRHPSLFKAI------GVKPPRGILMYGPPG 270
            :|:::|||...  ..:..|..:||:          ..|..|:.|      ..:|..|.    .||
  Fly   170 KEQQQSLNHPSELNREGDGQEQQLS----------NQPQRFRPIQPLEMAANRPGGGY----SPG 220

  Fly   271 TGKTLIARAVANETGAFFFLINGPEIMSKLAGESESNL---RKAFEEAEKNSPAIIFIDEIDA-- 330
            .|..|:|:...:...||.::....:|..:..|..|..:   ||..:|.|.......:....|.
  Fly   221 PGDPLLAKQKHHHRRAFEYISKALKIDEENEGHKELAIELYRKGIKELEDGIAVDCWSGRGDVWD 285

  Fly   331 ------------IAPKRDKTH--GEVERRIVSQLLTLMDGMK--------KSSHLIVMAATNRPN 373
                        ::..||:.|  ...|:.:..|.|:|.:..|        |:...::...||.|.
  Fly   286 RAQRLHDKMQTNLSMARDRLHFLALREQDLQMQRLSLKEKQKEEAQSKPQKTREPMLAGMTNEPM 350

  Fly   374 SIDPALRRFGRFDREIDIGIPDATGRLEVLRIHTKNMKLHDDVDLEQIAAESHGHVGADLASLCS 438
            .:  .:|..|...:......|.|:||  .|.|.:|.     .|:|  ..|.....:..:|.|..|
  Fly   351 KL--RVRSSGYGPKATTSAQPTASGR--KLTIGSKR-----PVNL--AVANKSQTLPRNLGSKTS 404

  Fly   439 EAALQQIREKMDLIDLEDDKIDAEVLASLAVTMENF-----------RYAMTKSSPSA------- 485
            ..|:|              :..|:..|:.......|           |..:..:.||.
  Fly   405 VGAVQ--------------RQPAKTAATPPAVRRQFSSGRNTPPQRSRTPINNNGPSGSGASTPV 455

  Fly   486 --------------LRETVVEVPNTTWTDIGGLESVKKELQELVQYPVEHPDKFLKFGMQ-PSRG 535
                          |.|.|.......||||.|.:..|:.|||:|..|...|:.|.  |:: |::|
  Fly   456 VSVKGVEQKLVQLILDEIVEGGAKVEWTDIAGQDVAKQALQEMVILPSVRPELFT--GLRAPAKG 518

  Fly   536 VLFYGPPGCGKTLLAKAIANECQANFISVKGPELLTMWFGESEANVRDIFDKARSAAPCVLFFDE 600
            :|.:||||.||||||:|:|.||.|.|:::....|.:.:.|:.|..||.:|..||...|.::|.||
  Fly   519 LLLFGPPGNGKTLLARAVATECSATFLNISAASLTSKYVGDGEKLVRALFAVARHMQPSIIFIDE 583

  Fly   601 LDSIAKARGGNVGDAGGAADRVINQILTEMDGMGAKKN---VFIIGATNRPDIIDPAILRPGRLD 662
            :||:...|..:..:   |:.|:..:.|.|.||:....:   :.::.|||||..:|.|.||  |..
  Fly   584 VDSLLSERSSSEHE---ASRRLKTEFLVEFDGLPGNPDGDRIVVLAATNRPQELDEAALR--RFT 643

  Fly   663 QLIYIPLPDDKSREAILKANLRK--SPLAKEVDLTYIAKVTQGFSGADLTEICQRACKLAIRQAI 725
            :.:|:.|||:::||.:|...|:|  |||..|. |..:||:|.|:||:|||.:.:.|....||:..
  Fly   644 KRVYVSLPDEQTRELLLNRLLQKQGSPLDTEA-LRRLAKITDGYSGSDLTALAKDAALEPIRELN 707

  Fly   726 EAEIRREKERAENQNSAMDMDEDDPVPEITSAHFEEAMKFARRSVSDNDIRKYEMFAQ 783
            ..:::           .:|:   ..:..||...|..::|..||||:...:..||.::|
  Fly   708 VEQVK-----------CLDI---SAMRAITEQDFHSSLKRIRRSVAPQSLNSYEKWSQ 751

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TER94	NP_001097249.1	CDC48	47..787	CDD:273521	167/643 (26%)
spas	NP_651206.3	MIT_spastin	230..308	CDD:239142	13/77 (17%)
		RecA-like_spastin	484..648	CDD:410932	62/170 (36%)
		AAA_lid_3	676..727	CDD:465537	16/64 (25%)
		Vps4_C	<722..754	CDD:462762	11/30 (37%)