DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment TER94 and trip13

DIOPT Version :9

Sequence 1:	NP_001097249.1	Gene:	TER94 / 36040	FlyBaseID:	FBgn0286784	Length:	826	Species:	Drosophila melanogaster
Sequence 2:	NP_956876.1	Gene:	trip13 / 393554	ZFINID:	ZDB-GENE-040426-1488	Length:	424	Species:	Danio rerio

Alignment Length:	383	Identity:	91/383 - (23%)
Similarity:	149/383 - (38%)	Gaps:	71/383 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   390 DIGI--PD----------ATGRLEVLRIHTKNMKLHDDVDLEQIAAESHGHVGADLASLCSEAAL 442
            |:||  ||          :|.:...:|.|..::     :|.......|...:..|...|....
Zfish    10 DVGIIRPDVHIEVHVKSQSTAKRSDVRTHVLSL-----LDRHSTVLRSFKWMDFDNEFLTKNV-- 67

  Fly   443 QQIREKMDLIDLEDDKIDAEVLASLAVTMENFRYAMTKSSPSAL---RETVVEVPNT-------- 496
                |.:.:.|:...|:....:.:|.:.:    :.:...|||.|   .|..:...|.
Zfish    68 ----ESVTIADVTGPKLVDLKVHNLCIHI----FTLNDDSPSTLNLEEEEELSAANLWLLPAVEF 124

  Fly   497 --TWTDIGGLESVKKELQELVQYPVEHPDKFLKFGMQP-SRGVLFYGPPGCGKTLLAKAIANE-- 556
              .|..:...|.:|.:|.:.|...:...||.:...:.. :|.||.:||||.|||.|.|.:|.:
Zfish   125 HGVWESLIYEEGIKTQLLDYVSTTIFFSDKNVDSNLIAWNRVVLLHGPPGTGKTSLCKGLAQKLS 189

  Fly   557 -------CQANFISVKGPELLTMWFGESEANVRDIFDKARSA-----APCVLFFDELDSIAKAR- 608
                   ..:.|:.:....|.:.||.||...|..:|.|.:..     |...:..||::|:..||
Zfish   190 IRLSDRYAHSQFVEINSHSLFSKWFSESGKLVTKMFQKIQELIDDKDALVFVLIDEVESLTAARS 254

  Fly   609 GGNVGDAGGAADRVINQILTEMDGMGAKKNVFIIGATNRPDIIDPAILRPGRLDQLIYIPLPDDK 673
            ....|.....|.||:|.:||::|.:....||.|:..:|..:.||.|.:  .|.|...||..|..|
Zfish   255 AAQAGTEPSDAIRVVNSVLTQLDQIKRHPNVVILTTSNVTEKIDLAFV--DRADIKQYIGPPSAK 317

  Fly   674 --------SREAILKANLRKSPLAKEVDLTYIAKVTQGFSGADLTEICQRACKLAIRQ 723
                    |.|.::|..: ..|..:.|.|..:.  |..|..:|:|.:  ..|.:.|.|
Zfish   318 AIFNIYLSSLEELMKRQI-IYPRQQLVSLEELE--TMNFMESDVTRL--SLCLMNISQ 370

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
TER94	NP_001097249.1	CDC48	47..787	CDD:273521	91/383 (24%)
		CDC48_N	47..129	CDD:280513
		CDC48_2	153..213	CDD:215011
		AAA	263..392	CDD:278434	1/1 (100%)
		AAA	536..669	CDD:278434	46/147 (31%)
		Vps4_C	<741..783	CDD:286426
trip13	NP_956876.1	AAA	164..314	CDD:214640	47/151 (31%)
trip13	NP_956876.1	AAA	167..312	CDD:278434	45/146 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0464
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810