DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment TER94 and Spata5l1

DIOPT Version :9

Sequence 1:	NP_001097249.1	Gene:	TER94 / 36040	FlyBaseID:	FBgn0286784	Length:	826	Species:	Drosophila melanogaster
Sequence 2:	NP_001028428.2	Gene:	Spata5l1 / 214616	MGIID:	3036261	Length:	747	Species:	Mus musculus

Alignment Length:	731	Identity:	243/731 - (33%)
Similarity:	387/731 - (52%)	Gaps:	96/731 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    85 RRKETVCIVLSDDTC--PDEKIRMNRVVRNNLCVHLSDVVSVQSCPDVKYGKRVRILPIDESTEG 147
            ||......|..|..|  |..::...|:.        .|.:....||.:   :|:.:.|:.....|
Mouse    64 RRDRVDGFVQLDPQCASPGARVATGRIG--------MDCLQPVPCPPL---RRLEVWPVLRPQAG 117

  Fly   148 VTGN--LFEIYLKPYFLEAYRPIHMGDNFIVRAAM-RPIEFKVVL---TDPEPYCIVAPETVIFC 206
            ...:  :.|:.   :.|...||:..|........: .|:....|:   .||||...|.|.|.|..
Mouse   118 APSSAAVLEVV---HELLRNRPVSRGHVVTTPPGVPGPVAALHVMGGTPDPEPGGWVTPHTRITL 179

  Fly   207 DGDPIKREEEEESLNAVGYDDIGGCRKQLAQIKEMVELPLRHPSLFKAIGVKPPRGILMYGPPGT 271
            ...|..:.|..      |...:||..:....::|::.||||:|....|:|:..|||:|:.||||.
Mouse   180 SDKPPPQVEPP------GEVTLGGLSETADSLRELLRLPLRYPLALAALGLAVPRGVLLAGPPGV 238

  Fly   272 GKTLIARAVANETGAFFFLINGPEIMSKLAGESESNLRKAFEEAEK---NSPAIIFIDEIDAIAP 333
            |||.:.||||.||||....::.|.:.....||:|.|:|:.|:.|::   ..|:::|:||:||:.|
Mouse   239 GKTQLVRAVARETGAELLAVSAPALQGSRPGETEENVRRIFQRAQELASRGPSLLFLDEVDALCP 303

  Fly   334 KRDKTHGEVERRIVSQLLTLMDGMKKSSHLIVMAATNRPNSIDPALRRFGRFDREIDIGIPDATG 398
            :|...|...|.|:|:|:|||:||:.:....:|:.|||||:.:||||||.||||||:.||.|....
Mouse   304 RRGGPHRAPESRVVAQVLTLLDGIHRDREFVVVGATNRPDELDPALRRPGRFDREVVIGTPTLKQ 368

  Fly   399 RLEVLRIHTKNMKLHDDVDLEQIAAESHGHVGADLASLCSEAALQQI--REKMDLIDLEDDKIDA 461
            |..:|::.|..|.:...:||..:|..:.|:|||||.:||.|||:..:  .||    :.:..||:.
Mouse   369 REAILQVITSKMPISSHIDLGLLAEMTVGYVGADLTALCREAAMCALLKNEK----NQDSPKIEE 429

  Fly   462 EVLASLAVTMENFRYAMTKSSPSALRET--VVEVPNTTWTDIGGLESVKKELQELVQYPVEHPDK 524
                      .:|..|..|..||:.|.:  ::::....|..|||||.||.:|::.|::|::.|.:
Mouse   430 ----------TDFLEAFKKIQPSSFRSSTGLMDIKPVGWEQIGGLEDVKLKLKQCVEWPLKFPQE 484

  Fly   525 FLKFGMQPSRGVLFYGPPGCGKTLLAKAIANECQANFISVKGPELLTMWFGESEANVRDIFDKAR 589
            |.:.|:...:|:|.||||||.||.|.:|:|..|..:|:||.|.:|.:.:.|:||..:..:|.:||
Mouse   485 FARMGLTQPKGLLLYGPPGCAKTTLVRALATGCHCSFVSVCGADLFSPFVGDSEKVLSQVFRQAR 549

  Fly   590 SAAPCVLFFDELDSIAKARGGNVGDAG-GAADRVINQILTEMDGMGAK----------------- 636
            :..|.::|.||:||:..:|  :||.:| .|.:||::.:|.|:||:|.:
Mouse   550 ANTPALVFLDEIDSVLGSR--SVGTSGCDARERVLSVLLNELDGVGVRTVERRGSKASQQECQEI 612

  Fly   637 --KNVFIIGATNRPDIIDPAILRPGRLDQLIYIPLPDDKSREAILKANLRKSPLAKEVDLTYIAK 699
              ::|.|:.||||||::|.|:|||||||::||:|.||.:.|.:|||......|:..:|.|..:|.
Mouse   613 LSRSVMIVVATNRPDVLDDALLRPGRLDKIIYVPPPDQEGRLSILKVCTNNMPVGPDVSLENLAA 677

  Fly   700 VTQGFSGADLTEICQRACKLAIRQ-AIEAEIRREKERAENQNSAMDMDEDDPVPEITSAHFEEAM 763
            .|..||||||..:|:.|...|::: .:||...|::                        ||.||:
Mouse   678 ETCFFSGADLRNLCKEAALFALQENGLEATTVRQE------------------------HFTEAL 718

  Fly   764 KFARRSVSDNDIRKYE 779
            |..:.|::..::..||
Mouse   719 KTVKPSLTLKELTFYE 734

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
TER94	NP_001097249.1	CDC48	47..787	CDD:273521	243/731 (33%)
		CDC48_N	47..129	CDD:280513	9/45 (20%)
		CDC48_2	153..213	CDD:215011	16/63 (25%)
		AAA	263..392	CDD:278434	60/131 (46%)
		AAA	536..669	CDD:278434	61/152 (40%)
		Vps4_C	<741..783	CDD:286426	8/39 (21%)
Spata5l1	NP_001028428.2	CDC48	14..738	CDD:273521	243/731 (33%)
		AAA	230..362	CDD:278434	60/131 (46%)
		AAA	496..646	CDD:278434	61/151 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D169540at33208
OrthoFinder	1	1.000	-	-		FOG0000137
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010