Protein Alignment eve and alx1

DIOPT Version :10

• Sequence 1: NP_523670.2
• Gene: eve / 36039
• FlyBaseID: FBgn0000606
• Length: 376
• Species: Drosophila melanogaster
• Sequence 2: NP_001038539.1
• Gene: alx1 / 565176
• ZFINID: ZDB-GENE-050419-191
• Length: 320
• Species: Danio rerio
• Alignment Length: 242
• Identity: 65/242 - (26%)
• Similarity: 100/242 - (41%)
• Gaps: 39/242 - (16%)

  Fly     5 RTYNMESHHAHHD---ASPVDQKPLVVDLLATQYGKPQTPPPS----PNEC-------LSSPDNS 55
            :.:.|:|:..|..   :||.|.:..|.      |..|::...|    .|.|       .|.||.:
Zfish    44 QAFPMQSNDQHSSMDRSSPCDNQSSVT------YCAPKSEESSLHAMENCCSLRVSPATSGPDKT 102

  Fly    56 LNGSRGSEIPADPS---VRRYRTAFTRDQLGRLEKEFYKENYVSRPRRCELAAQLNLPESTIKVW 117
            .....|.:..::.|   .||:||.||..||..|||.|.|.:|.....|.:||.:..|.|:.::||
Zfish   103 DLDELGEKCDSNVSSSKKRRHRTTFTSAQLEELEKVFQKTHYPDVYVREQLAMRTELTEARVQVW 167

  Fly   118 FQNRRMK-DKRQRIAVAWPYAAVYSDPAFAASILQAAANSVGMP----YPPYAPAAAAAAAAAAA 177
            |||||.| .||:|          |.....|.|...|..:...:|    |...:.......:|.::
Zfish   168 FQNRRAKWRKRER----------YGQIQQAKSHFAATYDISMLPRTDSYSQISNNLWTGPSAGSS 222

  Fly   178 VATNPMMATGMPPMGMPQMPTMQMPGHSGHAGHPSPYGQYRYTPYHI 224
            |.::.|:..|.||......|........|:.|.|: :.|.::...|:
Zfish   223 VVSSCMIPRGSPPCVTSPYPHSPRAAEHGYVGFPN-HQQNQFGVNHV 268

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eve	NP_523670.2	Homeodomain	71..127	CDD:459649	27/56 (48%)
alx1	NP_001038539.1	Homeodomain	121..177	CDD:459649	27/55 (49%)
		Transactivation domain. /evidence=ECO:0000250|UniProtKB:Q63087	180..320		19/100 (19%)
		OAR	296..314	CDD:461067
		OAR. /evidence=ECO:0000255|PROSITE-ProRule:PRU00138	300..313