Protein Alignment eve and PROP1

DIOPT Version :10

• Sequence 1: NP_523670.2
• Gene: eve / 36039
• FlyBaseID: FBgn0000606
• Length: 376
• Species: Drosophila melanogaster
• Sequence 2: NP_006252.4
• Gene: PROP1 / 5626
• HGNCID: 9455
• Length: 226
• Species: Homo sapiens
• Alignment Length: 214
• Identity: 61/214 - (28%)
• Similarity: 83/214 - (38%)
• Gaps: 47/214 - (21%)

  Fly    38 PQTPPPSPNECLSSPD-NSLNGSRGSEIPADP---------SVRRYRTAFTRDQLGRLEKEFYKE 92
            |.|..|:.....|:|. ..|.|:.|......|         |.||:||.|:..||.:||..|.:.
Human    27 PATGTPTTTVDSSAPPCRRLPGAGGGRSRFSPQGGQRGRPHSRRRHRTTFSPVQLEQLESAFGRN 91

  Fly    93 NYVSRPRRCELAAQLNLPESTIKVWFQNRRMKDKRQRIAVAWPYAAVYSDPAFAASIL---QAAA 154
            .|.....|..||....|.|:.|:|||||||.|.::|..::..|.|  :..||..:|.|   .|..
Human    92 QYPDIWARESLARDTGLSEARIQVWFQNRRAKQRKQERSLLQPLA--HLSPAAFSSFLPESTACP 154

  Fly   155 NSVGMPYP-------PYAPAAAAAAAAAAAVATNPMMATGMPPMGMPQMPTMQMPGHSGHAGHPS 212
            .|...|.|       ||:.|..:..:...|.|.:.......|.:                  ||:
Human   155 YSYAAPPPPVTCFPHPYSHALPSQPSTGGAFALSHQSEDWYPTL------------------HPA 201

  Fly   213 PYGQYRYTPYHIPARPAPP 231
            |.|       |:|..|.||
Human   202 PAG-------HLPCPPPPP 213

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eve	NP_523670.2	Homeodomain	71..127	CDD:459649	25/55 (45%)
PROP1	NP_006252.4	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..75		13/47 (28%)
		Homeodomain	70..126	CDD:459649	25/55 (45%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	196..226		10/43 (23%)