Protein Alignment eve and MSX2

DIOPT Version :10

• Sequence 1: NP_523670.2
• Gene: eve / 36039
• FlyBaseID: FBgn0000606
• Length: 376
• Species: Drosophila melanogaster
• Sequence 2: NP_002440.2
• Gene: MSX2 / 4488
• HGNCID: 7392
• Length: 267
• Species: Homo sapiens
• Alignment Length: 246
• Identity: 63/246 - (25%)
• Similarity: 100/246 - (40%)
• Gaps: 79/246 - (32%)

  Fly    20 PVDQKPLVVD----------LLATQYGKPQTPPPSPNECLSSP--------DNSLNGSRGSEIPA 66
            |.:..||..:          ||.:.:|..:...|.|   |..|        :||.:|:...:.|.
Human    59 PKEASPLPAESASAGATLRPLLLSGHGAREAHSPGP---LVKPFETASVKSENSEDGAAWMQEPG 120

  Fly    67 ---------DPSV---------RRYRTAFTRDQLGRLEKEFYKENYVSRPRRCELAAQLNLPEST 113
                     .|:.         |:.||.||..||..||::|.::.|:|...|.|.::.|||.|:.
Human   121 RYSPPPRHMSPTTCTLRKHKTNRKPRTPFTTSQLLALERKFRQKQYLSIAERAEFSSSLNLTETQ 185

  Fly   114 IKVWFQNRRMKDKRQRIAVAWPYAAVYSDPAFAASILQAAA-----NSVGMPYPPYAPAAAAAAA 173
            :|:||||||.|.||.:.|              ....|:.||     :|..:|:|..:|..||:..
Human   186 VKIWFQNRRAKAKRLQEA--------------ELEKLKMAAKPMLPSSFSLPFPISSPLQAASIY 236

  Fly   174 AAAAVATNPMMATGMPPMGMPQMPTMQMPGHSGHAGHPSPYGQYRYTPYHI 224
            .|:.....|::.  :||:|:                :.:|.|   |..||:
Human   237 GASYPFHRPVLP--IPPVGL----------------YATPVG---YGMYHL 266

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eve	NP_523670.2	Homeodomain	71..127	CDD:459649	26/55 (47%)
MSX2	NP_002440.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..71		3/11 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	116..147		3/30 (10%)
		Homeodomain	143..199	CDD:459649	26/55 (47%)