Protein Alignment eve and cdx1

DIOPT Version :10

• Sequence 1: NP_523670.2
• Gene: eve / 36039
• FlyBaseID: FBgn0000606
• Length: 376
• Species: Drosophila melanogaster
• Sequence 2: NP_989416.1
• Gene: cdx1 / 395055
• XenbaseID: XB-GENE-485396
• Length: 262
• Species: Xenopus tropicalis
• Alignment Length: 230
• Identity: 57/230 - (24%)
• Similarity: 81/230 - (35%)
• Gaps: 67/230 - (29%)

  Fly     8 NMESHHAH---------------HDASP----VDQKPLVVDLLATQYGKPQTP-----PPSPNEC 48
            |.:.||..               |...|    ....|..:....:.|...|.|     |||.|..
 Frog    50 NSDPHHGQPGGTWSSYTPSREDWHPYGPGPGASSANPAQISFSPSDYNPVQPPGPGLLPPSLNSS 114

  Fly    49 LS--SPD----NSLNGSRGSEIPADPSVR-------RYRTAFTRDQLGRLEKEFYKENYVSRPRR 100
            :|  ||.    |.....|.:.:|...:..       :||..:|..|...|||||:...|::..|:
 Frog   115 VSPLSPSAQRRNLYEWMRRTGVPTSTNSNGKTRTKDKYRVVYTDHQRLELEKEFHYSRYITIRRK 179

  Fly   101 CELAAQLNLPESTIKVWFQNRRMKD------KRQRIAVAWPYAAVYSDPAFAASILQAAANSVGM 159
            .||||.|.|.|..:|:||||||.|:      |.|:                     |:...|...
 Frog   180 AELAASLALTERQVKIWFQNRRAKERKVNKKKMQQ---------------------QSQQASTTT 223

  Fly   160 PYPPYAPAAAAAAAAAAAVATNPMMATGMPPMGMP 194
            |.||.....|......::.::|..:.:   |..||
 Frog   224 PTPPSVGTTAGMGGLCSSSSSNSNLVS---PSSMP 255

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eve	NP_523670.2	Homeodomain	71..127	CDD:459649	26/68 (38%)
cdx1	NP_989416.1	Caudal_act	13..141	CDD:461413	19/90 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	42..120		14/69 (20%)
		Homeodomain	151..206	CDD:459649	26/54 (48%)
		Interaction with DNA. /evidence=ECO:0000250|UniProtKB:P47902	152..173		9/20 (45%)
		Interaction with 5-mCpG DNA. /evidence=ECO:0000250|UniProtKB:P47902	191..202		6/10 (60%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	203..262		13/77 (17%)