Protein Alignment eve and BARHL2

DIOPT Version :10

• Sequence 1: NP_523670.2
• Gene: eve / 36039
• FlyBaseID: FBgn0000606
• Length: 376
• Species: Drosophila melanogaster
• Sequence 2: NP_064447.1
• Gene: BARHL2 / 343472
• HGNCID: 954
• Length: 387
• Species: Homo sapiens
• Alignment Length: 329
• Identity: 82/329 - (24%)
• Similarity: 106/329 - (32%)
• Gaps: 135/329 - (41%)

  Fly    12 HHAHHDAS---------------PVDQKPLVVDLLATQYGKPQTPPPSPNECL------------ 49
            ||.||...               |..|:||          .||.|||.|.:.|
Human    86 HHLHHSQQPPPPAAAPTQSLQPLPQQQQPL----------PPQQPPPPPPQQLGSAASAPRTSTS 140

  Fly    50 ------------------------SSP-------------------------------------- 52
                                    |||
Human   141 SFLIKDILGDSKPLAACAPYSTSVSSPHHTPKQESNAVHESFRPKLEQEDSKTKLDKREDSQSDI 205

  Fly    53 ---------DNSLNGSRGSEIPADPSVRRYRTAFTRDQLGRLEKEFYKENYVSRPRRCELAAQLN 108
                     |..:..||.|........|:.||||:..||.:||:.|.::.|:|...|.:|||.||
Human   206 KCHGTKEEGDREITSSRESPPVRAKKPRKARTAFSDHQLNQLERSFERQKYLSVQDRMDLAAALN 270

  Fly   109 LPESTIKVWFQNRRMKDKRQR------IAVAWPYAA---VYSDPAFAASILQAAANSVGMPYPPY 164
            |.::.:|.|:||||.|.|||.      :|.|..|:|   ::..|.|....|..:.:|
Human   271 LTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMFPSPYFYHPSLLGSMDS-------- 327

  Fly   165 APAAAAAAAAAAAVATNPMMATGMPPMGMPQMPTMQMPGHSGHAGHPSPYGQYRYTPYHIPARPA 229
                 ..||||||...:.|..|  ||...||:....:|....|.  ..|.||....|...|. |.
Human   328 -----TTAAAAAAAMYSSMYRT--PPAPHPQLQRPLVPRVLIHG--LGPGGQPALNPLSSPI-PG 382

  Fly   230 PPHP 233
            .|||
Human   383 TPHP 386

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eve	NP_523670.2	Homeodomain	71..127	CDD:459649	26/55 (47%)
BARHL2	NP_064447.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..145		15/68 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	157..240		11/82 (13%)
		Homeodomain	233..289	CDD:459649	26/55 (47%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	367..387		9/21 (43%)