Protein Alignment eve and HOXB5

DIOPT Version :10

• Sequence 1: NP_523670.2
• Gene: eve / 36039
• FlyBaseID: FBgn0000606
• Length: 376
• Species: Drosophila melanogaster
• Sequence 2: NP_002138.1
• Gene: HOXB5 / 3215
• HGNCID: 5116
• Length: 269
• Species: Homo sapiens
• Alignment Length: 152
• Identity: 50/152 - (32%)
• Similarity: 66/152 - (43%)
• Gaps: 36/152 - (23%)

  Fly     8 NMESHHAHHDA-SPVDQ--------------------KPLVVDLLATQYGKPQTPPPSPNECLSS 51
            |.:||.|...| ||.||                    :|   :..|:|...|......| |.:::
Human   104 NGDSHGAKPSASSPSDQATSASSSANFTEIDEASASSEP---EEAASQLSSPSLARAQP-EPMAT 164

  Fly    52 PDNSLNGSRGSEIP-----------ADPSVRRYRTAFTRDQLGRLEKEFYKENYVSRPRRCELAA 105
            ...:..|......|           ..|..:|.|||:||.|...|||||:...|::|.||.|:|.
Human   165 STAAPEGQTPQIFPWMRKLHISHDMTGPDGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAH 229

  Fly   106 QLNLPESTIKVWFQNRRMKDKR 127
            .|.|.|..||:||||||||.|:
Human   230 ALCLSERQIKIWFQNRRMKWKK 251

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eve	NP_523670.2	Homeodomain	71..127	CDD:459649	31/55 (56%)
HOXB5	NP_002138.1	PRK07003	<67..>171	CDD:235906	15/70 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	77..173		16/72 (22%)
		Antp-type hexapeptide	176..181		1/4 (25%)
		Homeodomain	195..251	CDD:459649	31/55 (56%)