Protein Alignment eve and HOXA5

DIOPT Version :10

• Sequence 1: NP_523670.2
• Gene: eve / 36039
• FlyBaseID: FBgn0000606
• Length: 376
• Species: Drosophila melanogaster
• Sequence 2: NP_061975.2
• Gene: HOXA5 / 3202
• HGNCID: 5106
• Length: 270
• Species: Homo sapiens
• Alignment Length: 191
• Identity: 53/191 - (27%)
• Similarity: 70/191 - (36%)
• Gaps: 84/191 - (43%)

  Fly    11 SHHAHHDASPVDQKPLVVDLLATQYGKPQT----PPPSPNECLS---SP--------DNSLNGSR 60
            |:.|...|:|.:.:          |.:|.|    |.|.|..|.:   ||        .|||:.|.
Human    72 SYAASASAAPAEPR----------YSQPATSTHSPQPDPLPCSAVAPSPGSDSHHGGKNSLSNSS 126

  Fly    61 GSEI----------------------------------------PADPSV--------------- 70
            |:..                                        ||.|.:
Human   127 GASADAGSTHISSREGVGTASGAEEDAPASSEQASAQSEPSPAPPAQPQIYPWMRKLHISHDNIG 191

  Fly    71 ----RRYRTAFTRDQLGRLEKEFYKENYVSRPRRCELAAQLNLPESTIKVWFQNRRMKDKR 127
                :|.|||:||.|...|||||:...|::|.||.|:|..|.|.|..||:||||||||.|:
Human   192 GPEGKRARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKK 252

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eve	NP_523670.2	Homeodomain	71..127	CDD:459649	31/55 (56%)
HOXA5	NP_061975.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	75..175		19/109 (17%)
		Antp-type hexapeptide	176..181		0/4 (0%)
		Homeodomain	196..252	CDD:459649	31/55 (56%)